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- Title
Reference values for the Cerebellar Cognitive Affective Syndrome Scale: age and education matter.
- Authors
Thieme, Andreas; Röske, Sandra; Faber, Jennifer; Sulzer, Patricia; Minnerop, Martina; Elben, Saskia; Reetz, Kathrin; Dogan, Imis; Barkhoff, Miriam; Konczak, Jürgen; Wondzinski, Elke; Siebler, Mario; Hetze, Susann; Müller, Oliver; Sure, Ulrich; Klockgether, Thomas; Synofzik, Matthis; Timmann, Dagmar
- Abstract
The original CCAS Scale was developed in a US cohort of 77 patients with various cerebellar diseases and 58 healthy controls (exploratory cohort) and was validated in another US cohort of 39 adult cerebellar patients and 55 healthy control subjects (validation cohort). The CCAS Scale consists of 12 test items that capture deficits in the core domains of CCAS. Age effects likely explain the differences in selectivity in our German study cohort compared to the validation cohort Figure 1 Age and education effects on CCAS Scale performance. A short and easily applicable bedside test (CCAS Scale), published by Hoche et al. (2018) in Brain, was developed to screen for CCAS and is already in widespread use.
- Subjects
WECHSLER Adult Intelligence Scale; REFERENCE values; AFFECT (Psychology); COGNITION disorders; COGNITION; CEREBELLUM diseases
- Publication
Brain: A Journal of Neurology, 2021, Vol 144, Issue 2, pe20
- ISSN
0006-8950
- Publication type
letter
- DOI
10.1093/brain/awaa417