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- Title
Generalized Peliosis Hepatis and Cirrhosis after Long-Term Use of Oral Contraceptives.
- Authors
Van Erpecum, K. J.; Janssens, A. R.; Kreuning, J.; Ruiter, D. J.; Kroon, H. M. J. A.; Grond, A. J. K.
- Abstract
Peliosis hepatis, a condition characterized by the presence of blood-filled lacunar spaces in the liver, has been described primarily in patients on androgenic steroid medication and patients with tuberculosis. It has never been reported as a complication of the use of oral contraceptives, except in association with and localized in contraceptive-induced hepatic tumors. The present report concerns a 43-yr-old woman with generalized peliosis hepatis that developed during long-term use of oral contraceptives. Extensive examination did not reveal a hepatic tumor. Liver cirrhosis and portal hypertension developed, although the oral contraceptives had been withdrawn. She finally underwent successfully an orthotopic liver transplantation.
- Subjects
PURPURA (Pathology); CIRRHOSIS of the liver; LIVER diseases; ORAL contraceptives; PORTAL hypertension; TUBERCULOSIS; STEROIDS
- Publication
American Journal of Gastroenterology (Springer Nature), 1988, Vol 83, Issue 5, p572
- ISSN
0002-9270
- Publication type
Article