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- Title
Mitochondrial Transfer as a Novel Therapeutic Approach in Disease Diagnosis and Treatment.
- Authors
Clemente-Suárez, Vicente Javier; Martín-Rodríguez, Alexandra; Yáñez-Sepúlveda, Rodrigo; Tornero-Aguilera, José Francisco
- Abstract
Mitochondrial dysfunction is a hallmark of numerous diseases, including neurodegenerative disorders, metabolic disorders, and cancer. Mitochondrial transfer, the transfer of mitochondria from one cell to another, has recently emerged as a potential therapeutic approach for restoring mitochondrial function in diseased cells. In this review, we summarize the current understanding of mitochondrial transfer, including its mechanisms, potential therapeutic applications, and impact on cell death pathways. We also discuss the future directions and challenges in the field of mitochondrial transfer as a novel therapeutic approach in disease diagnosis and treatment.
- Subjects
THERAPEUTICS; DIAGNOSIS; NEURODEGENERATION; CELL death; METABOLIC disorders
- Publication
International Journal of Molecular Sciences, 2023, Vol 24, Issue 10, p8848
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms24108848