We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Vitamin D and COVID-19: An Overview of Recent Evidence.
- Authors
Ghelani, Drishti; Alesi, Simon; Mousa, Aya
- Abstract
The novel coronavirus severe acute respiratory syndrome (SARS-CoV-2) has progressed rapidly from an outbreak to a global pandemic, with new variants rapidly emerging. Coronavirus disease 2019 (COVID-19), the disease resulting from SARS-CoV-2 infection, can lead to multiorgan damage. Due to the extremely contagious and fatal nature of the virus, it has been a priority of medical research to find effective means of treatment. Amid this search, the role of vitamin D in modulating various aspects of the innate and adaptive immune system has been discussed. This review aims to consolidate the research surrounding the role of vitamin D in the treatment and prevention of COVID-19. While there are some conflicting results reported, the consensus is that vitamin D has a host of immunomodulatory effects which may be beneficial in the context of COVID-19 and that low levels of vitamin D can result in dysfunction of crucial antimicrobial effects, potentially contributing to poor prognosis. Studies also show that the effects of low vitamin D can be mitigated via supplementation, although the benefits of vitamin D supplementation in the treatment of COVID-19 remain controversial.
- Subjects
COVID-19; VITAMIN D; SARS-CoV-2; COVID-19 treatment; DIETARY supplements
- Publication
International Journal of Molecular Sciences, 2021, Vol 22, Issue 19, p10559
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms221910559