We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Molecular Mechanisms of Sensorineural Hearing Loss and Development of Inner Ear Therapeutics.
- Authors
Vlajkovic, Srdjan M.; Thorne, Peter R.
- Abstract
Reduced activity of the KCNQ4 channel has been associated with a genetic form of hearing loss, noise-induced hearing loss, and age-related hearing loss [[11]]. In addition, the link between hearing loss and dementia has been established, with the view that hearing loss prevention may also protect cognitive function. Congenital hearing loss commonly manifests as hearing deficits at birth or during early development, while acquired hearing loss is usually sustained in later life from infection, exposure to excessive noise, ototoxic drugs, or the ageing process. There is a significant need for the development of effective therapies to prevent permanent cochlear damage and hearing loss after acoustic overexposure.
- Subjects
SENSORINEURAL hearing loss; INNER ear; THERAPEUTICS
- Publication
International Journal of Molecular Sciences, 2021, Vol 22, Issue 11, p5647
- ISSN
1661-6596
- Publication type
Editorial
- DOI
10.3390/ijms22115647