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- Title
Pápulas de Gottron. Alteraciones histológicas.
- Authors
Navarrete Franco, Gisela; Santa Cruz, Fermín Jurado; Maya Aranda, Susana Esther
- Abstract
Background: Dermatomyositis (DM) belongs to a group of diseases known as idiopathic inflammatory myopathies. It manifests by a proximal inflammatory myopathy of extensor muscles and pathognomonic skin lesions like Gottron's papules (GP). Nowadays, one of the most important aspects for the diagnosis continues to be muscular biopsy, although there are publications were it has been observed that histological alterations of the GP are more relevant to the diagnosis of DM. Objective: To determine the histological alterations of Gottron's papules. Material and methods: Retrospective, transversal, observational and descriptive study of 30 biopsies performed Center (Centro Dermatólogico Dr. Ladislao de la Pascua). Results: The histological characteristics found in GP allow the diagnosis of collagen vascular disease highlighting the importance of hydropic degeneration of the basal layer (HDBL; 60%) and thickening of the basal membrane (TBM; 56.7%). The most affected gender was the female (80%) and the highest incidence was found in the age groups 11-20 and 41-50 (bimodal distribution). Conclusions: It is necessary to perform a methodological design of diagnostic test with the objective of demonstrating that the sensibility and specificity is greater in the histopathological study of the GP than in the muscle biopsy, as it is observed in this pilot study.
- Subjects
DERMATOMYOSITIS; MUSCLE diseases; SKIN cancer; DISEASE incidence; VASCULAR diseases; RETROSPECTIVE studies; MEDICAL statistics
- Publication
Dermatología Revista Mexicana, 2013, Vol 57, Issue 2, p95
- ISSN
0185-4038
- Publication type
Article