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- Title
Allopurinol-induced DRESS syndrome.
- Authors
Yaylaci, Selcuk; Demir, Mustafa Volkan; Temiz, Tayfun; Tamer, Ali; Uslan, Mustafa Ihsan
- Abstract
A 70-year-old man was admitted to our clinic with complaints of fever, jaundice, dyspnea, and generalized rash after 3 months of allopurinol treatment for gout. On physical examination, he was found to have fever (38.5°C), jaundice, and generalized maculopapular rash. Leukocytosis, eosinophilia, elevation of liver enzymes, and hyperbilirubinemia were detected in his blood analysis. Skin biopsy was consistent with drug-induced hypersensitivity. He was diagnosed as Drug Rash with Eosinophilia and Systemic Symptoms (DRESS). Allopurinol treatment was stopped and steroid treatment was launched. At day 24 of admission, the patient died because of multiple organ failure.
- Subjects
BLOOD testing; BLOOD analysis laboratories; DYSPNEA; PULMONARY manifestations of general diseases; RESPIRATORY diseases
- Publication
Indian Journal of Pharmacology, 2012, Vol 44, Issue 3, p412
- ISSN
0253-7613
- Publication type
Article
- DOI
10.4103/0253-7613.96351