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- Title
Predictivity of acute kidney injury risk scores for late kidney injury in patients with chronic coronary syndrome.
- Authors
Saito, Yuichi; Deguchi, Yuki; Nakao, Motohiro; Shiraishi, Hirokazu; Sakamoto, Naoya; Kobayashi, Satoru; Kobayashi, Yoshio
- Abstract
Late rather than acute kidney injury after percutaneous coronary intervention (PCI) has been recently recognized as a predictor of future adverse events in patient with coronary artery disease. The risk-predicting models for acute kidney injury reported by Mehran et al., Bartholomew et al., and Tsai et al. were derived from a large cohort and externally validated, although the applicability of these models for predicting late kidney injury is unknown. A total of 327 patients undergoing elective PCI procedures were included. We calculated the three scores and tested their diagnostic ability for predicting late kidney injury (> 6 months after PCI), defined as an increase in creatinine levels ≥ 0.3 mg/dl or ≥ 50% from baseline. During the median follow-up period of 28 months, 27 (8.3%) patients had late kidney injury. All three scores significantly predicted late kidney injury, among which the score by Tsai et al. had a better diagnostic ability (area under the curve 0.83, best cut-off value 14, p < 0.001). With the best cut-off value, patients with Tsai score ≥ 14 had a significantly higher rate of late kidney injury than their counterpart (27.4% vs. 2.8%, p < 0.001). In conclusion, established risk scores for acute kidney injury may be useful for predicting late kidney injury after PCI in patients with chronic coronary syndrome.
- Subjects
ACUTE kidney failure; DISEASE risk factors; KIDNEY injuries; PERCUTANEOUS coronary intervention; KIDNEY transplantation; CORONARY artery disease; DRUG-eluting stents
- Publication
Heart & Vessels, 2022, Vol 37, Issue 12, p1971
- ISSN
0910-8327
- Publication type
Article
- DOI
10.1007/s00380-022-02105-z