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- Title
Surgical management of long intramedullary spinal cord tumors.
- Authors
Michael Tobias; Matthew McGirt; Kaisorn Chaichana; Ira Goldstein; Karl Kothbauer; Fred Epstein; George Jallo
- Abstract
Abstract Object  Spinal cord tumors represent approximately 10â20% of primary central nervous system tumors. Only 20â30% of primary intradural tumors are intramedullary. The incidence of longitudinally extensive tumors involving the cervical, thoracic, and lumbar spine is very low ( Materials and methods  We retrospectively reviewed all patients undergoing surgical resection of longitudinally extensive intramedullary spinal cord tumors involving the majority of the spinal cord between 1990 and 2002. Clinical, radiographic, operative, and outcome variables were retrospectively recorded and reported. Results  Thirteen patients (eight male, five female) were included in the study. Mean age was 15 years (range, 3â45) at the time of the initial resection. Gross total resection was achieved in eight cases and subtotal resection in five cases. Pathology revealed astrocytoma in six cases (two pilocytic, four grade II), gangliogliomas in four cases, oligodendroglioma in two cases (one anaplastic), and lipoma in one case. One (8%) patient died from progression of anaplastic oligodendroglioma, and two (15%) underwent reoperation for recurrent tumor (ganglioglioma, grade II astrocytoma). With a mean of 3.4 years (range, 1â12) after surgery, the modified McCormick score (MMS) had worsened in only two (15%) patients, improved in three (23%) patients, and remained stable in seven (54%) patients compared to preoperative MMS. Five (38%) patients required fusion for progressive spinal deformity. Conclusion  Gross total resection of holocord and longitudinally extensive intramedullary spinal cord tumors can be achieved with preservation of long-term neurological function in many cases. Serial imaging is recommended to guide subsequent resection for tumor recurrence and stabilization of progressive spinal deformity.
- Subjects
CENTRAL nervous system tumors; SURGICAL excision; CYSTS (Pathology); PREVENTIVE medicine
- Publication
Child's Nervous System, 2008, Vol 24, Issue 2, p219
- ISSN
0256-7040
- Publication type
Article
- DOI
10.1007/s00381-007-0405-7