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- Title
Systems biology: The cost of feedback control.
- Authors
Sun, Li; Becskei, Attila
- Abstract
The article discusses a research by Lestas and colleagues which establishes the limits of feedback control on noise suppression in molecular fluctuation through a theoritical analysis. It states that the stochastic control problem was modeled through information theory which is often used for fundamental limits in signal processing. It reveals that increasing the copy-number in the signalling circuitry compromise the external noise to transmit information in the feedback circuitry.
- Subjects
FEEDBACK control systems; NOISE control; MOLECULAR biology; STOCHASTIC analysis; INFORMATION theory; CALCULUS; SIGNAL processing
- Publication
Nature, 2010, Vol 467, Issue 7312, p163
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/467163a