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- Title
Antibacterial Activities of Phytofabricated ZnO and CuO NPs by Mentha pulegium Leaf/Flower Mixture Extract against Antibiotic Resistant Bacteria.
- Authors
Alavi, Mehran; Dehestaniathar, Saeed; Mohammadi, Shadieh; Maleki, Afshin; Karimi, Naser
- Abstract
Purpose: In this study, leaf/flower aqueous extract of medicinal plant species Mentha pulegium was used to synthesize ZnO and CuO nanoparticles (NPs) as a cost-effective, one-step, and eco-friendly method. Methods: Physicochemical properties of both metal oxide NPs (MONPs) were determined by UV-Vis spectroscopy, X-ray diffraction (XRD), Fourier-transform infrared (FTIR) spectroscopy, scanning electron microscope (SEM) and energy dispersive X-ray (EDX) techniques. Results: Phytofabricated ZnONPs and CuNPs illustrated 65.02±7.55 and 26.92±4.7 nm with antibacterial activities against antibiotic-resistant Escherichia coli and Staphylococcus aureus. Higher antibacterial activities were observed for CuONPs compared with ZnONPs. Conclusion: Large surface area and more reactivity resulted from smaller size as well as higher production of reactive oxygen species (ROS) were considered to antibacterial efficiency of CuONPs against antibiotic-resistant E. coli and S. aureus.
- Subjects
MINTS (Plants); ANTIBIOTICS; SCANNING electron microscopes; METALLIC oxides; REACTIVE oxygen species; PHENOLIC acids; ZINC oxide
- Publication
Advanced Pharmaceutical Bulletin, 2021, Vol 11, Issue 3, p497
- ISSN
2228-5881
- Publication type
Article
- DOI
10.34172/apb.2021.057