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- Title
genomicSimulation: fast R functions for stochastic simulation of breeding programs.
- Authors
Villiers, Kira; Dinglasan, Eric; Hayes, Ben J.; Voss-Fels, Kai P.
- Abstract
Simulation tools are key to designing and optimizing breeding programs that are multiyear, high-effort endeavors. Tools that operate on real genotypes and integrate easily with other analysis software can guide users toward crossing decisions that best balance genetic gains and genetic diversity required to maintain gains in the future. Here, we present genomicSimulation, a fast and flexible tool for the stochastic simulation of crossing and selection based on real genotypes. It is fully written in C for high execution speeds, has minimal dependencies, and is available as an R package for the integration with R's broad range of analysis and visualization tools. Comparisons of a simulated recreation of a breeding program to a real data set demonstrate the simulated offspring from the tool correctly show key population features, such as genomic relationships and approximate linkage disequilibrium patterns. Both versions of genomicSimulation are freely available on GitHub: The R package version at https://github.com/vllrs/genomicSimulation/ and the C library version at https://github.com/ vllrs/genomicSimulationC/.
- Subjects
SIMULATION software; LINKAGE disequilibrium; GENETIC variation; GENOTYPES; FORENSIC genetics
- Publication
G3: Genes | Genomes | Genetics, 2022, Vol 12, Issue 10, p1
- ISSN
2160-1836
- Publication type
Article
- DOI
10.1093/g3journal/jkac216