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- Title
Curative and adjuvant cancer treatment with exercise.
- Authors
Lim, Fiona; Lui, Louisa; Wan, Bo Angela; Lam, Henry; Silva, Maurício F.; Malek, Leila
- Abstract
Due to aging population, the number of patients diagnosed with cancer is expected to be increasing worldwide. Various cancer treatments were known to cause different morbidities in physical, functional and psychological aspects which can either be short term or long time lasting for years. All these adversely affect patient's daily activities, social life and overall quality of life. This review mainly focuses on patients receiving adjuvant treatments and the effects of exercise in modulating the above-mentioned treatmentrelated morbidities. A total of 15 articles were included after removal of duplicates and exclusion of studies based on pre-defined criteria. Currently available evidences suggested that exercise during cancer treatments was safe and feasible. Improvements were observed in objectivelymeasured outcomes include physical fitness, muscular strength and body composition. Few studies evaluated effect of exercise on treatment completion rate but all showed encouraging results with less likelihood and amount of chemotherapy dose reduction. Evidences on patientreported outcomes were less consistent except for reduction in cancer-related fatigue. Benefits in different sub-domains of health-related quality of life were demonstrated in different studies but not for overall quality of life, which could be explained by the complex interaction between physical, mental, social and functioning components in the overall well-being of patients. However, majority of studies had relatively short follow-up which ended at the time of completion of exercise program in which long term benefits from earlier exercise started during treatment period remained unanswered.
- Subjects
TUMOR treatment; BODY composition; ADJUVANT treatment of cancer; COMBINED modality therapy; EXERCISE; EXERCISE therapy; MUSCLE strength; PHYSICAL fitness; QUALITY of life; SYSTEMATIC reviews; CHEMORADIOTHERAPY
- Publication
Journal of Pain Management, 2018, Vol 11, Issue 3, p235
- ISSN
1939-5914
- Publication type
Article