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Model‐Informed Drug Development for Long‐Acting Injectable Products: Summary of American College of Clinical Pharmacology Symposium.
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- Clinical Pharmacology in Drug Development, 2021, v. 10, n. 3, p. 220, doi. 10.1002/cpdd.928
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- Article
PBPK Modeling Approach to Predict the Behavior of Drugs Cleared by Metabolism in Pregnant Subjects and Fetuses.
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- Pharmaceutics, 2024, v. 16, n. 1, p. 96, doi. 10.3390/pharmaceutics16010096
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- Publication type:
- Article
Comprehensive Physiologically Based Pharmacokinetic Model to Assess Drug–Drug Interactions of Phenytoin.
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- Pharmaceutics, 2023, v. 15, n. 10, p. 2486, doi. 10.3390/pharmaceutics15102486
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- Article
Leveraging Physiologically Based Modelling to Provide Insights on the Absorption of Paliperidone Extended-Release Formulation under Fed and Fasting Conditions.
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- Pharmaceutics, 2023, v. 15, n. 2, p. 629, doi. 10.3390/pharmaceutics15020629
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- Article
PBPK Modeling as a Tool for Predicting and Understanding Intestinal Metabolism of Uridine 5′-Diphospho-glucuronosyltransferase Substrates.
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- Pharmaceutics, 2021, v. 13, n. 9, p. 1325, doi. 10.3390/pharmaceutics13091325
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- Article
Physiologically Based Pharmacokinetic Absorption Model for Pexidartinib to Evaluate the Impact of Meal Contents and Intake Timing on Drug Exposure.
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- Clinical Pharmacology in Drug Development, 2024, v. 13, n. 4, p. 440, doi. 10.1002/cpdd.1385
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- Article
Clinical Ocular Exposure Extrapolation for Ophthalmic Solutions Using PBPK Modeling and Simulation.
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- Pharmaceutical Research, 2023, v. 40, n. 2, p. 431, doi. 10.1007/s11095-022-03390-z
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- Article
Ocular Physiologically Based Pharmacokinetic Modeling for Ointment Formulations.
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- Pharmaceutical Research, 2020, v. 37, n. 12, p. 1, doi. 10.1007/s11095-020-02965-y
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- Article
Binding of Matrix Metalloproteinase Inhibitors to Extracellular Matrix: 3D-QSAR Analysis.
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- Chemical Biology & Drug Design, 2008, v. 72, n. 4, p. 237, doi. 10.1111/j.1747-0285.2008.00710.x
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- Article
The Role of Model Master Files for Sharing, Acceptance, and Communication with FDA.
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- AAPS Journal, 2024, v. 26, n. 2, p. 1, doi. 10.1208/s12248-024-00897-8
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- Article
Long-Acting Injectable Aqueous Suspensions—Summary From an AAPS Workshop.
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- AAPS Journal, 2023, v. 25, n. 3, p. 1, doi. 10.1208/s12248-023-00811-8
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- Publication type:
- Article
PBPK Modeling Approach to Predict the Behavior of Drugs Cleared by Kidney in Pregnant Subjects and Fetus.
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- AAPS Journal, 2021, v. 23, n. 4, p. 1, doi. 10.1208/s12248-021-00603-y
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- Article
Application of Mechanistic Ocular Absorption Modeling and Simulation to Understand the Impact of Formulation Properties on Ophthalmic Bioavailability in Rabbits: a Case Study Using Dexamethasone Suspension.
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- AAPS Journal, 2019, v. 21, n. 4, p. 1, doi. 10.1208/s12248-019-0334-x
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- Article
Erratum to: Use of Modeling and Simulation Tools for Understanding the Impact of Formulation on the Absorption of a Low Solubility Compound: Ciprofloxacin.
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- 2016
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- Publication type:
- Erratum
Use of Modeling and Simulation Tools for Understanding the Impact of Formulation on the Absorption of a Low Solubility Compound: Ciprofloxacin.
- Published in:
- AAPS Journal, 2016, v. 18, n. 4, p. 886, doi. 10.1208/s12248-016-9913-2
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- Article
Development of a Novel Oral Cavity Compartmental Absorption and Transit Model for Sublingual Administration: Illustration with Zolpidem.
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- AAPS Journal, 2015, v. 17, n. 3, p. 631, doi. 10.1208/s12248-015-9727-7
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- Publication type:
- Article
Simulations of the Nonlinear Dose Dependence for Substrates of Influx and Efflux Transporters in the Human Intestine.
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- AAPS Journal, 2009, v. 11, n. 2, p. 353, doi. 10.1208/s12248-009-9111-6
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- Article
Prediction of Modified Release Pharmacokinetics and Pharmacodynamics from In Vitro, Immediate Release, and Intravenous Data.
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- AAPS Journal, 2009, v. 11, n. 2, p. 323, doi. 10.1208/s12248-009-9107-2
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- Publication type:
- Article
Public Workshop Summary Report on Fiscal Year 2021 Generic Drug Regulatory Science Initiatives: Data Analysis and Model‐Based Bioequivalence.
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- Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 5, p. 1190, doi. 10.1002/cpt.2120
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- Article
Clinical Ocular Exposure Extrapolation for a Complex Ophthalmic Suspension Using Physiologically Based Pharmacokinetic Modeling and Simulation.
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- 2024
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- Publication type:
- Case Study
Applying Physiologically Based Pharmacokinetic Modeling to Interpret Carbamazepine's Nonlinear Pharmacokinetics and Its Induction Potential on Cytochrome P450 3A4 and Cytochrome P450 2C9 Enzymes.
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- Pharmaceutics, 2024, v. 16, n. 6, p. 737, doi. 10.3390/pharmaceutics16060737
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- Publication type:
- Article
Development of Mechanistic In Vitro–In Vivo Extrapolation to Support Bioequivalence Assessment of Long-Acting Injectables.
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- Pharmaceutics, 2024, v. 16, n. 4, p. 552, doi. 10.3390/pharmaceutics16040552
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- Article
Quantitative clinical pharmacology for size and age scaling in pediatric drug development: A systematic review.
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- Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1207, doi. 10.1002/jcph.555
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- Publication type:
- Article
Development of PBPK model for intra-articular injection in human: methotrexate solution and rheumatoid arthritis case study.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2021, v. 48, n. 6, p. 909, doi. 10.1007/s10928-021-09781-w
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- Article
Physiologically Based Pharmacokinetic Modelling for First-In-Human Predictions: An Updated Model Building Strategy Illustrated with Challenging Industry Case Studies.
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- 2019
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- Publication type:
- journal article
Correction to: Predicting Human Dermal Drug Concentrations Using PBPK Modeling and Simulation: Clobetasol Propionate Case Study.
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- 2024
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- Publication type:
- Correction Notice
Predicting Human Dermal Drug Concentrations Using PBPK Modeling and Simulation: Clobetasol Propionate Case Study.
- Published in:
- AAPS PharmSciTech, 2024, v. 25, n. 3, p. 1, doi. 10.1208/s12249-024-02740-x
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- Publication type:
- Article
Drug–drug interaction prediction of ziritaxestat using a physiologically based enzyme and transporter pharmacokinetic network interaction model.
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- CTS: Clinical & Translational Science, 2023, v. 16, n. 11, p. 2222, doi. 10.1111/cts.13622
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- Publication type:
- Article
Effect of Hepatic Impairment on Trofinetide Exposures Using an In Silico Physiologically Based Pharmacokinetic Model.
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- Advances in Therapy, 2024, v. 41, n. 8, p. 3328, doi. 10.1007/s12325-024-02926-6
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- Publication type:
- Article