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Functional characterization of ABCC2 promoter polymorphisms and allele-specific expression.
Published in:
Pharmacogenomics Journal, 2013, v. 13, n. 5, p. 396, doi. 10.1038/tpj.2012.20
By:
- Nguyen, T D;
- Markova, S;
- Liu, W;
- Gow, J M;
- Baldwin, R M;
- Habashian, M;
- Relling, M V;
- Ratain, M J;
- Kroetz, D L
Publication type:
Article
Cytochrome P450 2D6 and glutathione S-transferase genotype in sudden infant death syndrome.
Published in:
1997
By:
- CHEN, CL;
- LIU, Q;
- EVANS, WE;
- SANDER, CH;
- RELLING, MV;
- Chen, C L;
- Evans, W E;
- Sander, C H;
- Relling, M V
Publication type:
journal article
Removal of methotrexate, leucovorin, and their metabolites by combined hemodialysis and hemoperfusion.
Published in:
1988
By:
- Relling, Mary V.;
- Stapleton, F. Bruder;
- Ochs, Judith;
- Jones, Deborah P.;
- Meyer, William;
- Wainer, Irving W.;
- Crom, William R.;
- McKay, Charles P.;
- Evans, William E.;
- Relling, M V;
- Stapleton, F B;
- Ochs, J;
- Jones, D P;
- Meyer, W;
- Wainer, I W;
- Crom, W R;
- McKay, C P;
- Evans, W E
Publication type:
journal article
Erratum: Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells.
Published in:
2003
By:
- Cheok, M H;
- Yang, W;
- Pui, C-H;
- Downing, J R;
- Cheng, C;
- Naeve, C W;
- Relling, M V;
- Evans, W E
Publication type:
Correction Notice
Infants with acute lymphoblastic leukemia: no evidence for high methotrexate resistance.
Published in:
Leukemia (08876924), 2002, v. 16, n. 5, p. 949, doi. 10.1038/sj.leu.2402491
By:
- Ramakers-van Woerden, N L;
- Pieters, R;
- Rots, M G;
- van Zantwijk, C H;
- Noordhuis, P;
- Beverloo, H B;
- Peters, G J;
- van Wering, E R;
- Camitta, B M;
- Pui, C-H;
- Relling, M V;
- Evans, W E;
- Veerman, A J P
Publication type:
Article
Magnetic resonance imaging detection of avascular necrosis of the bone in children receiving intensive prednisone therapy for acute lymphoblastic leukemia or non-Hodgkin lymphoma.
Published in:
2001
By:
- Ribeiro, R C;
- Fletcher, B D;
- Kennedy, W;
- Harrison, P L;
- Neel, M D;
- Kaste, S C;
- Sandlund, J T;
- Rubnitz, J E;
- Razzouk, B I;
- Relling, M V;
- Pui, C-H
Publication type:
journal article
International Childhood Acute Lymphoblastic Leukemia Workshop: Sausalito, CA, 30 November-1 December 2000.
Published in:
2001
By:
- Pui, C-H;
- Sallan, S;
- Relling, M V;
- Masera, G;
- Evans, W E
Publication type:
journal article
Long-term results of Total Therapy studies 11, 12 and 13A for childhood acute lymphoblastic leukemia at St Jude Children's Research Hospital.
Published in:
2000
By:
- Pui, C-H;
- Boyett, J M;
- Rivera, G K;
- Hancock, M L;
- Sandlund, J T;
- Ribeiro, R C;
- Rubnitz, J E;
- Behm, F G;
- Raimondi, S C;
- Gajjar, A;
- Razzouk, B;
- Campana, D;
- Kun, L E;
- Relling, M V;
- Evans, W E
Publication type:
journal article
Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia.
Published in:
2000
By:
- McLeod, H L;
- Krynetski, E Y;
- Relling, M V;
- Evans, W E
Publication type:
journal article
Glutathione S-transferase genotypes in children who develop treatment-related acute myeloid malignancies.
Published in:
2000
By:
- Woo, M H;
- Shuster, J J;
- Chen, C;
- Bash, R O;
- Behm, F G;
- Camitta, B;
- Felix, C A;
- Kamen, B A;
- Pui, C-H;
- Raimondi, S C;
- Winick, N J;
- Amylon, M D;
- Relling, M V
Publication type:
journal article
Individualized methotrexate dosing in children with relapsed acute lymphoblastic leukemia.
Published in:
2000
By:
- Wall, A M;
- Gajjar, A;
- Link, A;
- Mahmoud, H;
- Pui, C-H;
- Relling, M V
Publication type:
journal article
Low frequency of TEL-AML1 in relapsed acute lymphoblastic leukemia supports a favorable prognosis for this genetic subgroup.
Published in:
1999
By:
- Rubnitz, J E;
- Behm, F G;
- Wichlan, D;
- Ryan, C;
- Sandlund, J T;
- Ribeiro, R C;
- Rivera, G K;
- Hancock, M L;
- Relling, M V;
- Evans, W E;
- Pui, C-H;
- Downing, J R
Publication type:
journal article
Anti-asparaginase antibodies following E. coli asparaginase therapy in pediatric acute lymphoblastic leukemia.
Published in:
1998
By:
- Woo, M H;
- Hak, L J;
- Storm, M C;
- Evans, W E;
- Sandlund, J T;
- Rivera, G K;
- Wang, B;
- Pui, C-H;
- Relling, M V
Publication type:
journal article
Transient encephalopathy following high-dose methotrexate treatment in childhood acute lymphoblastic leukemia.
Published in:
1998
By:
- Rubnitz, J E;
- Relling, M V;
- Harrison, P L;
- Sandlund, J T;
- Ribeiro, R C;
- Rivera, G K;
- Thompson, S J;
- Evans, W E;
- Pui, C-H
Publication type:
journal article
Etoposide and antimetabolite pharmacology in patients who develop secondary acute myeloid leukemia.
Published in:
1998
By:
- Relling, M V;
- Yanishevski, Y;
- Nemec, J;
- Evans, W E;
- Boyett, J M;
- Behm, F G;
- Pui, C-H
Publication type:
journal article
Urate oxidase in prevention and treatment of hyperuricemia associated with lymphoid malignancies.
Published in:
1997
By:
- Pui, C-H;
- Relling, M V;
- Lascombes, F;
- Harrison, P L;
- Struxiano, A;
- Mondesir, J-M;
- Ribeiro, R C;
- Sandlund, J T;
- Rivera, G K;
- Evans, W E;
- Mahmoud, H H
Publication type:
journal article
Genetic studies of childhood acute lymphoblastic leukemia with emphasis on p16, MLL, and ETV6 gene abnormalities: results of St Jude Total Therapy Study XII.
Published in:
1997
By:
- Rubnitz, J E;
- Behm, F G;
- Pui, C-H;
- Evans, W E;
- Relling, M V;
- Raimondi, S C;
- Harrison, P L;
- Sandlund, J T;
- Ribeiro, R C;
- Grosveld, G;
- Downing, J R
Publication type:
journal article
Pharmacogenetics: Call to Action.
Published in:
2011
By:
- Relling, M. V.;
- Guchelaar, H. J.;
- Roden, D. M.;
- Klein, T. E.
Publication type:
Letter
Functional Characterization of Liver Enhancers That Regulate Drug-Associated Transporters.
Published in:
Clinical Pharmacology & Therapeutics, 2011, v. 89, n. 4, p. 571, doi. 10.1038/clpt.2010.353
By:
- Kim, M. J.;
- Skewes-Cox, P.;
- Fukushima, H.;
- Hesselson, S.;
- Yee, S. W.;
- Ramsey, L. B.;
- Nguyen, L.;
- Eshragh, J. L.;
- Castro, R. A.;
- Wen, C. C.;
- Stryke, D.;
- Johns, S. J.;
- Ferrin, T. E.;
- Kwok, P.-Y.;
- Relling, M. V.;
- Giacomini, K. M.;
- Kroetz, D. L.;
- Ahituv, N.
Publication type:
Article
Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing.
Published in:
Clinical Pharmacology & Therapeutics, 2011, v. 89, n. 3, p. 387, doi. 10.1038/clpt.2010.320
By:
- Relling, M. V.;
- Gardner, E. E.;
- Sandborn, W. J.;
- Schmiegelow, K.;
- Pui, C.-H.;
- Yee, S. W.;
- Stein, C. M.;
- Carrillo, M.;
- Evans, W. E.;
- Klein, T. E.
Publication type:
Article
CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network.
Published in:
Clinical Pharmacology & Therapeutics, 2011, v. 89, n. 3, p. 464, doi. 10.1038/clpt.2010.279
By:
- Relling, M. V.;
- Klein, T. E.
Publication type:
Article
Promoter Polymorphisms in the β-2 Adrenergic Receptor Are Associated With Drug-Induced Gene Expression Changes and Response in Acute Lymphoblastic Leukemia.
Published in:
Clinical Pharmacology & Therapeutics, 2010, v. 88, n. 6, p. 854, doi. 10.1038/clpt.2010.212
By:
- Pottier, N.;
- Paugh, S. W.;
- Ding, C.;
- Pei, D.;
- Yang, W.;
- Das, S.;
- Cook, E. H.;
- Pui, C.-H.;
- Relling, M. V.;
- Cheok, M. H.;
- Evans, W. E.
Publication type:
Article
Genetic Variations in GRIA1 on Chromosome 5q33 Related to Asparaginase Hypersensitivity.
Published in:
Clinical Pharmacology & Therapeutics, 2010, v. 88, n. 2, p. 191, doi. 10.1038/clpt.2010.94
By:
- Chen, S.-H.;
- Pei, D.;
- Yang, W.;
- Cheng, C.;
- Jeha, S.;
- Cox, N. J.;
- Evans, W. E.;
- Pui, C.-H.;
- Relling, M. V.
Publication type:
Article
Comparison of Native E. coli and PEG Asparaginase Pharmacokinetics and Pharmacodynamics in Pediatric Acute Lymphoblastic Leukemia.
Published in:
Clinical Pharmacology & Therapeutics, 2009, v. 86, n. 6, p. 651, doi. 10.1038/clpt.2009.162
By:
- Panetta, J. C.;
- Gajjar, A.;
- Hijiya, N.;
- Hak, L. J.;
- Cheng, C.;
- Liu, W.;
- Pui, C. H.;
- Relling, M. V.
Publication type:
Article
Genetic Polymorphism of Inosine Triphosphate Pyrophosphatase Is a Determinant of Mercaptopurine Metabolism and Toxicity During Treatment for Acute Lymphoblastic Leukemia.
Published in:
Clinical Pharmacology & Therapeutics, 2009, v. 85, n. 2, p. 164, doi. 10.1038/clpt.2008.154
By:
- Stocco, G.;
- Cheok, M. H.;
- Crews, K. R.;
- Dervieux, T.;
- French, D.;
- Pei, D.;
- Yang, W.;
- Cheng, C.;
- Pui, C.-H.;
- Relling, M. V.;
- Evans, W. E.
Publication type:
Article
Etoposide Sensitivity Does Not Predict MLL Rearrangements or Risk of Therapy-Related Acute Myeloid Leukemia.
Published in:
Clinical Pharmacology & Therapeutics, 2008, v. 84, n. 6, p. 691, doi. 10.1038/clpt.2008.86
By:
- Yang, J.;
- Bogni, A.;
- Cheng, C.;
- Bleibel, W. K.;
- Cai, X.;
- Fan, Y.;
- Yang, W.;
- Rocha, J. C. C.;
- Pei, D.;
- Liu, W.;
- M. E.Dolan;
- Pui, C.-H.;
- Relling, M. V.
Publication type:
Article
Using HapMap Tools in Pharmacogenomic Discovery: The Thiopurine Methyltransferase Polymorphism.
Published in:
Clinical Pharmacology & Therapeutics, 2007, v. 81, n. 5, p. 729, doi. 10.1038/sj.clpt.6100135
By:
- Jones, T. S.;
- Yang, W.;
- Evans, W. E.;
- Relling, M. V.
Publication type:
Article
The Pharmacogenetics Research Network: From SNP Discovery to Clinical Drug Response.
Published in:
Clinical Pharmacology & Therapeutics, 2007, v. 81, n. 3, p. 328, doi. 10.1038/sj.clpt.6100087
By:
- Giacomini, K. M.;
- Brett, C. M.;
- Altman, R. B.;
- Benowitz, N. L.;
- Dolan, M. E.;
- Flockhart, D. A.;
- Johnson, J. A.;
- Hayes, D. F.;
- Klein, T.;
- Krauss, R. M.;
- Kroetz, D. L.;
- McLeod, H. L.;
- Nguyen, A. T.;
- Ratain, M. J.;
- Relling, M. V.;
- Reus, V.;
- Roden, D. M.;
- Schaefer, C. A.;
- Shuldiner, A. R.;
- Skaar, T.
Publication type:
Article
Should Pharmacogenomic Studies be Required for New Drug Approval?
Published in:
Clinical Pharmacology & Therapeutics, 2007, v. 81, n. 3, p. 425, doi. 10.1038/sj.clpt.6100097
By:
- Relling, M. V.;
- Hoffman, J. M.
Publication type:
Article
Use of CPT-11 as an in vitro phenotypic probe for CYP3A4/CYP3A5 activity.
Published in:
Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 2, p. P61, doi. 10.1016/S0009-9236(03)90582-0
By:
- Ramirez, J.;
- Innocenti, F.;
- Rivory, L. P.;
- Relling, M. V.;
- Schuetz, E. G.;
- Ratain, M. J.
Publication type:
Article
Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus.
Published in:
1999
By:
- Relling, Mary V.;
- Hancock, Michael L.;
- Relling, M V;
- Hancock, M L;
- Rivera, G K;
- Sandlund, J T;
- Ribeiro, R C;
- Krynetski, E Y;
- Pui, C H;
- Evans, W E
Publication type:
journal article
Relationship between cytotoxicity and site-specific DNA recombination after in vitro exposure of leukemia cells to etoposide.
Published in:
1996
By:
- Chen CL;
- Fuscoe JC;
- Liu Q;
- Pui CH;
- Mahmoud HH;
- Relling MV;
- Chen, C L;
- Fuscoe, J C;
- Liu, Q;
- Pui, C H;
- Mahmoud, H H;
- Relling, M V
Publication type:
journal article
Comparison of the Guidelines of the Clinical Pharmacogenetics Implementation Consortium and the Dutch Pharmacogenetics Working Group.
Published in:
Clinical Pharmacology & Therapeutics, 2018, v. 103, n. 4, p. 599, doi. 10.1002/cpt.762
By:
- Bank, P. C. D.;
- Caudle, K. E.;
- Swen, J. J.;
- Gammal, R. S.;
- Whirl‐Carrillo, M.;
- Klein, T. E.;
- Relling, M. V.;
- Guchelaar, H‐J
Publication type:
Article
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Rasburicase Therapy in the Context of G6PD Deficiency Genotype.
Published in:
Clinical Pharmacology & Therapeutics, 2014, v. 96, n. 2, p. 169, doi. 10.1038/clpt.2014.97
By:
- Relling, M V;
- McDonagh, E M;
- Chang, T;
- Caudle, K E;
- McLeod, H L;
- Haidar, C E;
- Klein, T;
- Luzzatto, L
Publication type:
Article
The Role of Inherited TPMT and COMT Genetic Variation in Cisplatin-Induced Ototoxicity in Children With Cancer.
Published in:
Clinical Pharmacology & Therapeutics, 2013, v. 94, n. 2, p. 252, doi. 10.1038/clpt.2013.121
By:
- Yang, J J;
- Lim, J Y S;
- Huang, J;
- Bass, J;
- Wu, J;
- Wang, C;
- Fang, J;
- Stewart, E;
- Harstead, E H;
- E, S;
- Robinson, G W;
- Evans, W E;
- Pappo, A;
- Zuo, J;
- Relling, M V;
- Onar‐Thomas, A;
- Gajjar, A;
- Stewart, C F
Publication type:
Article
The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Overcoming Challenges of Real-World Implementation.
Published in:
Clinical Pharmacology & Therapeutics, 2013, v. 94, n. 2, p. 207, doi. 10.1038/clpt.2013.59
By:
- Shuldiner, A R;
- Relling, M V;
- Peterson, J F;
- Hicks, K;
- Freimuth, R R;
- Sadee, W;
- Pereira, N L;
- Roden, D M;
- Johnson, J A;
- Klein, T E
Publication type:
Article
Clinical Implementation of Pharmacogenetics: More than One Gene at a Time.
Published in:
Clinical Pharmacology & Therapeutics, 2013, v. 93, n. 5, p. 384, doi. 10.1038/clpt.2013.7
By:
- Johnson, J A;
- Klein, T E;
- Relling, M V
Publication type:
Article
Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing: 2013 Update.
Published in:
Clinical Pharmacology & Therapeutics, 2013, v. 93, n. 4, p. 324, doi. 10.1038/clpt.2013.4
By:
- Relling, M V;
- Gardner, E E;
- Sandborn, W J;
- Schmiegelow, K;
- Pui, C‐H;
- Yee, S W;
- Stein, C M;
- Carrillo, M;
- Evans, W E;
- Hicks, J K;
- Schwab, M;
- Klein, T E
Publication type:
Article
A Clinician-Driven Automated System for Integration of Pharmacogenetic Interpretations Into an Electronic Medical Record.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 5, p. 563, doi. 10.1038/clpt.2012.140
By:
- Hicks, J K;
- Crews, K R;
- Hoffman, J M;
- Kornegay, N M;
- Wilkinson, M R;
- Lorier, R;
- Stoddard, A;
- Yang, W;
- Smith, C;
- Fernandez, C A;
- Cross, S J;
- Haidar, C;
- Baker, D K;
- Howard, S C;
- Evans, W E;
- Broeckel, U;
- Relling, M V
Publication type:
Article
Pharmacogenomics and Individualized Medicine: Translating Science Into Practice.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 4, p. 467, doi. 10.1038/clpt.2012.120
By:
- Crews, K R;
- Hicks, J K;
- Pui, C-H;
- Relling, M V;
- Evans, W E
Publication type:
Article
Concordance of DMET Plus Genotyping Results With Those of Orthogonal Genotyping Methods.
Published in:
Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 3, p. 360, doi. 10.1038/clpt.2012.95
By:
- Fernandez, C A;
- Smith, C;
- Yang, W;
- Lorier, R;
- Crews, K R;
- Kornegay, N;
- Hicks, J K;
- Stewart, C F;
- Kawedia, J D;
- Ramsey, L B;
- Liu, C;
- Evans, W E;
- Relling, M V;
- Broeckel, U
Publication type:
Article
The effect of atovaquone on etoposide pharmacokinetics in children with acute lymphoblastic leukemia.
Published in:
2001
By:
- van de Poll, Matthijs E.;
- Relling, Mary V.;
- Schuetz, Erin G.;
- Harrison, Patricia L.;
- Hughes, Walter;
- Flynn, Patricia M.;
- van de Poll, M E;
- Relling, M V;
- Schuetz, E G;
- Harrison, P L;
- Hughes, W;
- Flynn, P M
Publication type:
journal article
A revised definition for cure of childhood acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2014, v. 28, n. 12, p. 2336, doi. 10.1038/leu.2014.142
By:
- Pui, C H;
- Pei, D;
- Campana, D;
- Cheng, C;
- Sandlund, J T;
- Bowman, W P;
- Hudson, M M;
- Ribeiro, R C;
- Raimondi, S C;
- Jeha, S;
- Howard, S C;
- Bhojwani, D;
- Inaba, H;
- Rubnitz, J E;
- Metzger, M L;
- Gruber, T A;
- Coustan-Smith, E;
- Downing, J R;
- Leung, W H;
- Relling, M V
Publication type:
Article
Clinical utility and implications of asparaginase antibodies in acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2012, v. 26, n. 11, p. 2303, doi. 10.1038/leu.2012.102
By:
- Liu, C;
- Kawedia, J D;
- Cheng, C;
- Pei, D;
- Fernandez, C A;
- Cai, X;
- Crews, K R;
- Kaste, S C;
- Panetta, J C;
- Bowman, W P;
- Jeha, S;
- Sandlund, J T;
- Evans, W E;
- Pui, C-H;
- Relling, M V
Publication type:
Article
ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy.
Published in:
Leukemia (08876924), 2012, v. 26, n. 2, p. 265, doi. 10.1038/leu.2011.227
By:
- Bhojwani, D;
- Pei, D;
- Sandlund, J T;
- Jeha, S;
- Ribeiro, R C;
- Rubnitz, J E;
- Raimondi, S C;
- Shurtleff, S;
- Onciu, M;
- Cheng, C;
- Coustan-Smith, E;
- Bowman, W P;
- Howard, S C;
- Metzger, M L;
- Inaba, H;
- Leung, W;
- Evans, W E;
- Campana, D;
- Relling, M V;
- Pui, C-H
Publication type:
Article
A genome-wide approach identifies that the aspartate metabolism pathway contributes to asparaginase sensitivity.
Published in:
2011
By:
- Chen, S.-H.;
- Yang, W.;
- Fan, Y.;
- Stocco, G.;
- Crews, K. R.;
- Yang, J. J.;
- Paugh, S. W.;
- Pui, C.-H.;
- Evans, W. E.;
- Relling, M. V.
Publication type:
journal article
ARID5B SNP rs10821936 is associated with risk of childhood acute lymphoblastic leukemia in blacks and contributes to racial differences in leukemia incidence.
Published in:
2010
By:
- Yang, W.;
- Treviño, L. R.;
- Yang, J. J.;
- Scheet, P.;
- Pui, C.-H.;
- Evans, W. E.;
- Relling, M. V.;
- Treviño, L R
Publication type:
Letter
Long-term results of St Jude Total Therapy Studies 11, 12, 13A, 13B, and 14 for childhood acute lymphoblastic leukemia.
Published in:
2010
By:
- Pui, C. H.;
- Pei, D.;
- Sandlund, J. T.;
- Ribeiro, R. C.;
- Rubnitz, J. E.;
- Raimondi, S. C.;
- Onciu, M.;
- Campana, D.;
- Kun, L. E.;
- Jeha, S.;
- Cheng, C.;
- Howard, S. C.;
- Metzger, M. L.;
- Bhojwani, D.;
- Downing, J. R.;
- Evans, W. E.;
- Relling, M. V.
Publication type:
journal article
Increased risk for CNS relapse in pre-B cell leukemia with the t(1;19)/TCF3-PBX1.
Published in:
2009
By:
- Jeha, S.;
- Pei, D.;
- Raimondi, S. C.;
- Onciu, M.;
- Campana, D.;
- Cheng, C.;
- Sandlund, J. T.;
- Ribeiro, R. C.;
- Rubnitz, J. E.;
- Howard, S. C.;
- Downing, J. R.;
- Evans, W. E.;
- Relling, M. V.;
- Pui, C.-H.
Publication type:
journal article
Genome scan implicates adhesion biological pathways in secondary leukemia.
Published in:
Leukemia (08876924), 2007, v. 21, n. 10, p. 2128, doi. 10.1038/sj.leu.2404885
By:
- Hartford, C.;
- Yang, W.;
- Cheng, C.;
- Fan, Y.;
- Liu, W.;
- Treviño, L.;
- Pounds, S.;
- Neale, G.;
- Raimondi, S. C.;
- Bogni, A.;
- Dolan, M. E.;
- Pui, C.-H.;
- Relling, M. V.
Publication type:
Article

Found: 57