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- Title
Delivery and assessment of endovascular stents to repair aortic coarctation using MR and X-ray imaging.
- Authors
Saeed, Maythem; Henk, Christine B.; Weber, Oliver; Martin, Alastair; Wilson, Mark; Shunk, Kendrick; Saloner, David; Higgins, Charles B.
- Abstract
<bold>Purpose: </bold>To investigate the utility of MR and X-ray imaging for characterizing aortic coarctation and flow, and guiding the endovascular catheter to place a stent to repair the coarctation. <bold>Materials and Methods: </bold>The descending aorta in eight dogs was looped with elastic band and tightened distal to the subclavian artery. Balanced fast field echo (bFFE) and velocity-encoded cine (VEC) MRI sequences were used for device tracking and measuring aortic flow. A T1-weighted fast-field echo sequence (T1-FFE) was used to visualize the coarctation and roadmap the aorta. Nitinol stents were guided by a nitinol guidewire and placed under MR guidance. <bold>Results: </bold>Aortic coarctation was visible on MR and X-ray imaging. The procedure success rate was 88%. VEC MRI measured the changes in aortic flow (baseline = 1.3 +/- 0.2, coarctation = 0.2 +/- 0.02, and stent placement = 0.8 +/- 0.1 liters/minute). A significant reduction in iliac blood pressure was measured after coarctation, but it was reversed by stent placement. The stent lumen was visible on X-ray fluoroscopy, but not on MRI. <bold>Conclusion: </bold>Stent deployment to repair aortic coarctation is feasible under MR guidance. The combined use of MR and X-ray imaging is effective for anatomic and functional evaluation of aortic coarctation dilation, which may be crucial for optimal therapy.
- Publication
Journal of Magnetic Resonance Imaging, 2006, Vol 24, Issue 2, p371
- ISSN
1053-1807
- Publication type
journal article
- DOI
10.1002/jmri.20631