We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
HYPOTHÈSE SUR LA RÉÉMERGENCE DU VIRUS BTV-8 EN 2015, EN FRANCE.
- Authors
Stéphan, Zientara; Corinne, Sailleau; Lydie, Postic; Grégory, Caignard; Aurore, Fablet; Damien, Vitour; Emmanuel, Bréard
- Abstract
Bluetongue virus serotype 8 (BTV-8), a midge-transmitted arbovirus, emerged in northern Europe in 2006 and spread to most European countries until 2010. Although the outbreak was successfully controlled by vaccination in early 2010, the BTV-8 strain re-emerged in France in 2015, triggering a second epizootic that continues today. The origin of this virus and the mechanism of its re-emergence were unknown. In this study and in collaboration with European partners, we performed phylogenetic analyses of 164 complete BTV-8 genomes sequenced directly from blood samples of naturally infected ruminants during the two epizootics from 2006 to 2010 and from 2015 to 2018. A consistent and linear genetic evolution of the virus is demonstrated during each epizootic and reflects the average rate at which BTV-8 accumulates mutations. However, the sequence of the strain at the origin of the 2015 wave is similar to a virus from the first wave (2006-2010), which abruptly interrupted its evolution around March 2008. The use of contaminated semen, kept during several years, for insemination of cattle herds, so-called private breeding, could explain the re-emergence of BTV8 in 2015.
- Publication
Épidémiologie et Santé Animale, 2022, Issue 79, p27
- ISSN
0754-2186
- Publication type
Article