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- Title
DEVELOPMENT AND VALIDATION RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF LEVOSULPIRIDE AND ILAPRAZOLE IN PHARMACEUTICAL DOSAGE FORM.
- Authors
Yadav, Rashmi R.; Shah, Darshil B.; Maheshwari, Dilip G.
- Abstract
RP-HPLC method Chromatographic separation of LSP and ILA were performed by use of isocratic mobile phase prepared from Phosphate buffer: Methanol: ACN (pH 3.8 adjusts with 10% ortho phosphoric acid) (35:45:20). Absorbance is measured at wavelength 294nm. Flow rate is 1 ml/min and Run time is 10 min. The average retention time was found to be 2.353 min and 4.85min for LSP and ILA respectively. Calibration curve was linear in concentration range of 1-5μg/mL for ILA and 7.5-37.5μg/mL for LSP. %RSD for precision was found to be less than 2% and the % recovery was found to between 98-102%.
- Subjects
DRUG dosage; DRUG efficacy; DRUG administration
- Publication
International Journal of Chemical & Pharmaceutical Analysis, 2016, Vol 3, Issue 3, p1
- ISSN
2348-0726
- Publication type
Article