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- Title
Myeloid sarcoma in a newborn: A rare manifestation of congenital acute myeloid leukemia.
- Authors
Mullen, Brooke; Sabet, Kazuhiro; Jacobs, Shana; Calleroz, Amanda Theresa; Habeshian, Kaiane Anoush; Cheng, Jinjun
- Abstract
Cutaneous myeloid sarcoma is rarely present prior to the diagnosis of congenital acute myeloid leukemia (AML); the former is typically diagnosed with or after the leukemia. We report a 2‐day‐old male born with multiple cutaneous red to violaceous nodules. Histopathologic and immunohistochemistry findings from a skin nodule were suspicious for myeloid sarcoma. Bone marrow biopsy was initially negative for aberrant blasts; however, at age 4 months, AML with a KMT2A gene rearrangement was identified via bone marrow biopsy.
- Subjects
ACUTE myeloid leukemia; MYELOID sarcoma; BONE marrow; NEWBORN infants; GENE rearrangement
- Publication
Pediatric Dermatology, 2023, Vol 40, Issue 4, p751
- ISSN
0736-8046
- Publication type
Article
- DOI
10.1111/pde.15313