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- Title
Two Cases of Cushing’s Syndrome Due to Overuse of Topical Steroid in the Diaper Area.
- Authors
Semiz, Serap; Balcı, Yasemin Işık; Ergin, Şeniz; Candemir, Maşallah; Polat, Aziz
- Abstract
Topical use of corticosteroids may cause immunosuppression and iatrogenic Cushing’s syndrome via hypothalamic-pituitary-adrenal axis. We report two cases with iatrogenic Cushing’s syndrome with different clinical outcomes due to abuse of same potent topical steroid clobetasol propionate. One of them died because of fatal disseminated cytomegalovirus infection. The other patient recovered completely. Physicians and parents should be informed about the adverse effects of such potent topical corticosteroids and physicians should prescribe less potent agents, especially during infancy.
- Subjects
CUSHING'S syndrome treatment; IATROGENIC diseases; ADRENOCORTICAL hormones; IMMUNOSUPPRESSION; STEROID drugs; THERAPEUTICS
- Publication
Pediatric Dermatology, 2008, Vol 25, Issue 5, p544
- ISSN
0736-8046
- Publication type
Article
- DOI
10.1111/j.1525-1470.2008.00735.x