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Age, JAK2(V617F) and SF3B1 mutations are the main predicting factors for survival in refractory anaemia with ring sideroblasts and marked thrombocytosis.
Published in:
2013
By:
- Broséus, J;
- Alpermann, T;
- Wulfert, M;
- Florensa Brichs, L;
- Jeromin, S;
- Lippert, E;
- Rozman, M;
- Lifermann, F;
- Grossmann, V;
- Haferlach, T;
- Germing, U;
- Luño, E;
- Girodon, F;
- Schnittger, S;
- MPN and MPNr-EuroNet (COST Action BM0902)
Publication type:
journal article
High incidence of RAS signalling pathway mutations in MLL-rearranged acute myeloid leukemia.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1933, doi. 10.1038/leu.2013.90
By:
- Grossmann, V;
- Schnittger, S;
- Poetzinger, F;
- Kohlmann, A;
- Stiel, A;
- Eder, C;
- Fasan, A;
- Kern, W;
- Haferlach, T;
- Haferlach, C
Publication type:
Article
Novel recurrent mutations in the RAS-like GTP-binding gene RIT1 in myeloid malignancies.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1943, doi. 10.1038/leu.2013.179
By:
- Gómez-Seguí, I;
- Makishima, H;
- Jerez, A;
- Yoshida, K;
- Przychodzen, B;
- Miyano, S;
- Shiraishi, Y;
- Husseinzadeh, H D;
- Guinta, K;
- Clemente, M;
- Hosono, N;
- McDevitt, M A;
- Moliterno, A R;
- Sekeres, M A;
- Ogawa, S;
- Maciejewski, J P
Publication type:
Article
Salvage therapy with azacitidine increases regulatory T cells in peripheral blood of patients with AML or MDS and early relapse after allogeneic blood stem cell transplantation.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1910, doi. 10.1038/leu.2013.64
By:
- Schroeder, T;
- Fröbel, J;
- Cadeddu, R-P;
- Czibere, A;
- Dienst, A;
- Platzbecker, U;
- Bug, G;
- Uharek, L;
- Fenk, R;
- Germing, U;
- Kröger, N;
- Haas, R;
- Kobbe, G
Publication type:
Article
RUNX1 meets MLL: epigenetic regulation of hematopoiesis by two leukemia genes.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1793, doi. 10.1038/leu.2013.200
By:
- Koh, C P;
- Wang, C Q;
- Ng, C E L;
- Ito, Y;
- Araki, M;
- Tergaonkar, V;
- Huang, G;
- Osato, M
Publication type:
Article
Suppression of Pu.1 function results in expanded myelopoiesis in zebrafish.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1913, doi. 10.1038/leu.2013.67
By:
- Sun, J;
- Liu, W;
- Li, L;
- Chen, J;
- Wu, M;
- Zhang, Y;
- Leung, A Y H;
- Zhang, W;
- Wen, Z;
- Liao, W
Publication type:
Article
CSF3R T618I is a highly prevalent and specific mutation in chronic neutrophilic leukemia.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1870, doi. 10.1038/leu.2013.122
By:
- Pardanani, A;
- Lasho, T L;
- Laborde, R R;
- Elliott, M;
- Hanson, C A;
- Knudson, R A;
- Ketterling, R P;
- Maxson, J E;
- Tyner, J W;
- Tefferi, A
Publication type:
Article
Phase I study of ON 01910.Na (Rigosertib), a multikinase PI3K inhibitor in relapsed/refractory B-cell malignancies.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1920, doi. 10.1038/leu.2013.79
By:
- Roschewski, M;
- Farooqui, M;
- Aue, G;
- Wilhelm, F;
- Wiestner, A
Publication type:
Article
Autoimmunity and persistent RAS-mutated clones long after the spontaneous regression of JMML.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1926, doi. 10.1038/leu.2013.82
By:
- Takagi, M;
- Piao, J;
- Lin, L;
- Kawaguchi, H;
- Imai, C;
- Ogawa, A;
- Watanabe, A;
- Akiyama, K;
- Kobayashi, C;
- Mori, M;
- Ko, K;
- Sugimoto, M;
- Mizutani, S
Publication type:
Article
Why do we see JAK2 exon 12 mutations in myeloproliferative neoplasms?
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1930, doi. 10.1038/leu.2013.85
By:
- Vorechovsky, I;
- Jones, A V;
- Cross, N C P
Publication type:
Article
Nilotinib treatment-associated accelerated atherosclerosis: when is the risk justified?
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1939, doi. 10.1038/leu.2013.112
By:
- Tefferi, A
Publication type:
Article
Combination of Azacitidine and Lenalidomide in Myelodysplastic Syndromes or acute Myeloid Leukemia-a wise Liaison?
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1813, doi. 10.1038/leu.2013.140
By:
- Platzbecker, U;
- Germing, U
Publication type:
Article
Acute erythroid leukemia (AEL) can be separated into distinct prognostic subsets based on cytogenetic and molecular genetic characteristics.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1940, doi. 10.1038/leu.2013.144
By:
- Grossmann, V;
- Bacher, U;
- Haferlach, C;
- Schnittger, S;
- Pötzinger, F;
- Weissmann, S;
- Roller, A;
- Eder, C;
- Fasan, A;
- Zenger, M;
- Staller, M;
- Kern, W;
- Kohlmann, A;
- Haferlach, T
Publication type:
Article
Mutations and prognosis in primary myelofibrosis.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1861, doi. 10.1038/leu.2013.119
By:
- Vannucchi, A M;
- Lasho, T L;
- Guglielmelli, P;
- Biamonte, F;
- Pardanani, A;
- Pereira, A;
- Finke, C;
- Score, J;
- Gangat, N;
- Mannarelli, C;
- Ketterling, R P;
- Rotunno, G;
- Knudson, R A;
- Susini, M C;
- Laborde, R R;
- Spolverini, A;
- Pancrazzi, A;
- Pieri, L;
- Manfredini, R;
- Tagliafico, E
Publication type:
Article
AKT is a therapeutic target in myeloproliferative neoplasms.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1882, doi. 10.1038/leu.2013.167
By:
- Khan, I;
- Huang, Z;
- Wen, Q;
- Stankiewicz, M J;
- Gilles, L;
- Goldenson, B;
- Schultz, R;
- Diebold, L;
- Gurbuxani, S;
- Finke, C M;
- Lasho, T L;
- Koppikar, P;
- Pardanani, A;
- Stein, B;
- Altman, J K;
- Levine, R L;
- Tefferi, A;
- Crispino, J D
Publication type:
Article
Age, JAK2<sup>V617F</sup> and SF3B1 mutations are the main predicting factors for survival in refractory anaemia with ring sideroblasts and marked thrombocytosis.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1826, doi. 10.1038/leu.2013.120
By:
- Broséus, J;
- Alpermann, T;
- Wulfert, M;
- Florensa Brichs, L;
- Jeromin, S;
- Lippert, E;
- Rozman, M;
- Lifermann, F;
- Grossmann, V;
- Haferlach, T;
- Germing, U;
- Luño, E;
- Girodon, F;
- Schnittger, S
Publication type:
Article
Impact of IKZF1 deletions and PAX5 amplifications in pediatric B-cell precursor ALL treated according to NOPHO protocols.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1936, doi. 10.1038/leu.2013.92
By:
- Öfverholm, I;
- Tran, A N;
- Heyman, M;
- Zachariadis, V;
- Nordenskjöld, M;
- Nordgren, A;
- Barbany, G
Publication type:
Article
Survival and prognosis among 1545 patients with contemporary polycythemia vera: an international study.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1874, doi. 10.1038/leu.2013.163
By:
- Tefferi, A;
- Rumi, E;
- Finazzi, G;
- Gisslinger, H;
- Vannucchi, A M;
- Rodeghiero, F;
- Randi, M L;
- Vaidya, R;
- Cazzola, M;
- Rambaldi, A;
- Gisslinger, B;
- Pieri, L;
- Ruggeri, M;
- Bertozzi, I;
- Sulai, N H;
- Casetti, I;
- Carobbio, A;
- Jeryczynski, G;
- Larson, D R;
- Müllauer, L
Publication type:
Article
SETBP1 mutations occur in 9% of MDS/MPN and in 4% of MPN cases and are strongly associated with atypical CML, monosomy 7, isochromosome i(17)(q10), ASXL1 and CBL mutations.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1852, doi. 10.1038/leu.2013.133
By:
- Meggendorfer, M;
- Bacher, U;
- Alpermann, T;
- Haferlach, C;
- Kern, W;
- Gambacorti-Passerini, C;
- Haferlach, T;
- Schnittger, S
Publication type:
Article
Prediction of poor outcome in CLL patients following first-line treatment with fludarabine, cyclophosphamide and rituximab.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1949, doi. 10.1038/leu.2013.190
By:
- Fink, A M;
- Böttcher, S;
- Ritgen, M;
- Fischer, K;
- Pflug, N;
- Eichhorst, B;
- Wendtner, C-M;
- Winkler, D;
- Bühler, A;
- Zenz, T;
- Staib, P;
- Mayer, J;
- Hensel, M;
- Hopfinger, G;
- Wenger, M;
- Fingerle-Rowson, G;
- Döhner, H;
- Kneba, M;
- Stilgenbauer, S;
- Busch, R
Publication type:
Article
A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1917, doi. 10.1038/leu.2013.77
By:
- Mupo, A;
- Celani, L;
- Dovey, O;
- Cooper, J L;
- Grove, C;
- Rad, R;
- Sportoletti, P;
- Falini, B;
- Bradley, A;
- Vassiliou, G S
Publication type:
Article
Epigenetics in clinical practice: the examples of azacitidine and decitabine in myelodysplasia and acute myeloid leukemia.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1803, doi. 10.1038/leu.2013.173
By:
- Estey, E H
Publication type:
Article
Applicability of a reproducible flow cytometry scoring system in the diagnosis of refractory cytopenia of childhood.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1923, doi. 10.1038/leu.2013.81
By:
- Aalbers, A M;
- van den Heuvel-Eibrink, M M;
- de Haas, V;
- te Marvelde, J G;
- de Jong, A X;
- van der Burg, M;
- Dworzak, M;
- Hasle, H;
- Locatelli, F;
- De Moerloose, B;
- Schmugge, M;
- Stary, J;
- Zecca, M;
- Zwaan, C M;
- van de Loosdrecht, A A;
- van Dongen, J J M;
- Niemeyer, C M;
- van der Velden, V H J
Publication type:
Article
Detailed molecular characterisation of acute myeloid leukaemia with a normal karyotype using targeted DNA capture.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1820, doi. 10.1038/leu.2013.117
By:
- Conte, N;
- Varela, I;
- Grove, C;
- Manes, N;
- Yusa, K;
- Moreno, T;
- Segonds-Pichon, A;
- Bench, A;
- Gudgin, E;
- Herman, B;
- Bolli, N;
- Ellis, P;
- Haddad, D;
- Costeas, P;
- Rad, R;
- Scott, M;
- Huntly, B;
- Bradley, A;
- Vassiliou, G S
Publication type:
Article
Toll-like receptor alterations in myelodysplastic syndrome.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1832, doi. 10.1038/leu.2013.180
By:
- Wei, Y;
- Dimicoli, S;
- Bueso-Ramos, C;
- Chen, R;
- Yang, H;
- Neuberg, D;
- Pierce, S;
- Jia, Y;
- Zheng, H;
- Wang, H;
- Wang, X;
- Nguyen, M;
- Wang, S A;
- Ebert, B;
- Bejar, R;
- Levine, R;
- Abdel-Wahab, O;
- Kleppe, M;
- Ganan-Gomez, I;
- Kantarjian, H
Publication type:
Article
Mobilization studies in C3-deficient mice unravel the involvement of a novel crosstalk between the coagulation and complement cascades in mobilization of hematopoietic stem/progenitor cells.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1928, doi. 10.1038/leu.2013.84
By:
- Borkowska, S;
- Suszynska, M;
- Wysoczynski, M;
- Ratajczak, M Z
Publication type:
Article
The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in core-binding factor acute myeloid leukemia.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1891, doi. 10.1038/leu.2013.186
By:
- Allen, C;
- Hills, R K;
- Lamb, K;
- Evans, C;
- Tinsley, S;
- Sellar, R;
- O'Brien, M;
- Yin, J L;
- Burnett, A K;
- Linch, D C;
- Gale, R E
Publication type:
Article
Oral lenalidomide with rituximab in relapsed or refractory diffuse large cell, follicular and transformed lymphoma: a phase II clinical trial.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1902, doi. 10.1038/leu.2013.95
By:
- Wang, M;
- Fowler, N;
- Wagner-Bartak, N;
- Feng, L;
- Romaguera, J;
- Neelapu, S S;
- Hagemeister, F;
- Fanale, M;
- Oki, Y;
- Pro, B;
- Shah, J;
- Thomas, S;
- Younes, A;
- Hosing, C;
- Zhang, L;
- Newberry, K J;
- Desai, M;
- Cheng, N;
- Badillo, M;
- Bejarano, M
Publication type:
Article
Insufficient stromal support in MDS results from molecular and functional deficits of mesenchymal stromal cells.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1841, doi. 10.1038/leu.2013.193
By:
- Geyh, S;
- Öz, S;
- Cadeddu, R-P;
- Fröbel, J;
- Brückner, B;
- Kündgen, A;
- Fenk, R;
- Bruns, I;
- Zilkens, C;
- Hermsen, D;
- Gattermann, N;
- Kobbe, G;
- Germing, U;
- Lyko, F;
- Haas, R;
- Schroeder, T
Publication type:
Article
Mutation of the colony-stimulating factor-3 receptor gene is a rare event with poor prognosis in chronic myelomonocytic leukemia.
Published in:
Leukemia (08876924), 2013, v. 27, n. 9, p. 1946, doi. 10.1038/leu.2013.182
By:
- Kosmider, O;
- Itzykson, R;
- Chesnais, V;
- Lasho, T;
- Laborde, R;
- Knudson, R;
- Gauthier, A;
- Merlevede, J;
- Ades, L;
- Morabito, M;
- Fontenay, M;
- Tefferi, A;
- Droin, N;
- Solary, E
Publication type:
Article

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