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- Title
Participation in a clinical trial is associated with lower mortality but not lower risk of HF hospitalization in patients with heart failure: observations from the ESC EORP Heart Failure Long-Term Registry.
- Authors
Kapelios, Chris J; Benson, Lina; Crespo-Leiro, Maria G; Anker, Stefan D; Coats, Andrew J S; Chioncel, Ovidiu; Filippatos, Gerasimos; Lainscak, Mitja; McDonagh, Theresa; Mebazaa, Alexandre; Metra, Marco; Piepoli, Massimo F; Rosano, Giuseppe M C; Ruschitzka, Frank; Savarese, Gianluigi; Seferovic, Petar M; Volterrani, Maurizio; Maggioni, Aldo P; Lund, Lars H
- Abstract
Keywords: Randomized controlled trial; Clinical trial; Trial design; Registry; Heart failure; Reduced ejection fraction; Mildly reduced ejection fraction; Preserved ejection fraction; Outcomes; Mortality; Heart failure hospitalization EN Randomized controlled trial Clinical trial Trial design Registry Heart failure Reduced ejection fraction Mildly reduced ejection fraction Preserved ejection fraction Outcomes Mortality Heart failure hospitalization 1526 1529 4 05/03/23 20230501 NES 230501 Randomized controlled trials (RCTs) form the basis for guidelines, regulatory approval, and reimbursement.[1] They are commonly industry-funded and apply selective eligibility criteria,[2] potentially limiting generalizability. Real-world heart failure management in 10,910 patients with chronic heart failure in the Netherlands: design and rationale of the chronic heart failure ESC guideline-based cardiology practice quality project (CHECK-HF) registry.
- Subjects
HEART failure; HEART failure patients; BRAIN natriuretic factor; CORONARY artery bypass; CLINICAL trials
- Publication
European Heart Journal, 2023, Vol 44, Issue 17, p1526
- ISSN
0195-668X
- Publication type
Article
- DOI
10.1093/eurheartj/ehad109