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- Title
Altered BCR and CD40 signalling are associated with clinical outcome in small lymphocytic lymphoma/chronic lymphocytic leukaemia and marginal zone lymphoma patients.
- Authors
Blix, Egil S.; Irish, Jonathan M.; Husebekk, Anne; Delabie, Jan; Tierens, Anne M.; Myklebust, June H.; Kolstad, Arne
- Abstract
The article presents information on a study related to the link between small lymphocytic leukemia (SLL) and B-cell receptor (BCR) and CD40 signaling. It informs about impairment in signaling lymphoma B cells after BCR stimulation and alteration in signaling patterns of signaling through BCR and CD40 that helps in predicting the outcome of SLL, chronic lymphocytic leukemia and marginal zone lymphoma.
- Subjects
LYMPHOMAS; B cells; CD40 antigen; CHRONIC lymphocytic leukemia; CELL receptors; CELLULAR signal transduction
- Publication
British Journal of Haematology, 2012, Vol 159, Issue 5, p0
- ISSN
0007-1048
- Publication type
Article
- DOI
10.1111/bjh.12073