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- Title
How Does Change in Depressive Symptomatology Influence Weight Change in Patients With Diabetes? Observational Results From the Pathways Longitudinal Cohort.
- Authors
Ludman, Evette J.; Russo, Joan E.; Katon, Wayne J.; Simon, Gregory E.; Williams, Lisa H.; Lin, Elizabeth H. B.; Heckbert, Susan R.; Ciechanowski, Paul; Young, Bessie A.
- Abstract
Background: Little is known about how change in depressive symptoms over time is associated with change in weight. Methods. Longitudinal associations between change in depression (Patient Health Questionnaire-9 [PHQ-9]) and weight (self-reported and chart abstracted) were examined in 2,600 patients with type 2 diabetes (mean age 62, SD-11.6) who were surveyed by telephone in 2001-2002 and 5 years later as part of the Pathways study. Mixed effects regression analyses compared a) patients with persistently low depression symptoms with those whose depression worsened (increased at least 5 points on PHQ-9) over 5 years and b) patients with persistently high depression symptoms with those who improved (decreased at least 5 points on PHQ-9) over 5 years. Results. Those who worsened in comparison to those with persistently low depression symptoms did not differ in their pattern of weight change (z=1.54, p = .12). Both groups weighed approximately 92 kg at baseline and lost approximately 2 kg. A significantly different pattern of change over time was observed for those with persistently high depression symptoms in comparison to those whose depression improved (z=1.98, p=.04). Although the groups had almost identical weight at baseline (approximately 100 kg), at the 5-year assessment, those with persistently high depression symptoms had about half the weight loss (M= -1.71, SD=9.08) in comparison to those whose depression improved (M= -3.62, SD= 19.93). Conclusion. In persons with diabetes who have clinically significant levels of depressive symptoms, improvement in depression is accompanied by significantly greater, clinically significant weight loss.
- Subjects
PEOPLE with diabetes; TYPE 2 diabetes &; psychology; DEPRESSED persons; BODY weight -- Risk factors; HEALTH; PHYSIOLOGY
- Publication
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2010, Vol 65A, Issue 1, p93
- ISSN
1079-5006
- Publication type
Article
- DOI
10.1093/gerona/glp151