We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Developing a Technique for the Imaging-Based Measurement of ACL Elongation: A Proof of Principle.
- Authors
Csapo, Robert; Heinrich, Dieter; Vigotsky, Andrew D.; Marx, Christian; Sinha, Shantanu; Fink, Christian
- Abstract
Towards the goal of obtaining non-invasive biomarkers reflecting the anterior cruciate ligament's (ACL) loading capacity, this project aimed to develop a magnetic resonance imaging (MRI)-based method facilitating the measurement of ACL elongations during the execution of knee stress tests. An MRI-compatible, computer-controlled, and pneumatically driven knee loading device was designed to perform Lachman-like tests and induce ACL strain. A human cadaveric leg was used for test purposes. During the execution of the stress tests, a triggered real-time cine MRI sequence with a temporal resolution of 10 Hz was acquired in a parasagittal plane to capture the resultant ACL elongations. To test the accuracy of these measurements, the results were compared to in situ data of ACL elongation that were acquired by measuring the length changes of a surgical wire directly sutured to the ACL's anteromedial bundle. The MRI-based ACL elongations ranged between 0.7 and 1.7 mm and agreed very well with in situ data (root mean square errors, RMSEs ≤ 0.25 mm), although peak elongation rates were underestimated by the MRI (RMSEs 0.19–0.36 mm/s). The high accuracy of elongation measurements underlines the potential of the technique to yield an imaging-based biomarker of the ACL's loading capacity.
- Subjects
MAGNETIC resonance imaging; ANTERIOR cruciate ligament; PROOF of concept; STANDARD deviations; ANTERIOR cruciate ligament injuries; SUTURING
- Publication
Diagnostics (2075-4418), 2021, Vol 11, Issue 11, p2126
- ISSN
2075-4418
- Publication type
Article
- DOI
10.3390/diagnostics11112126