We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Pharmacotherapy in relieving the symptoms of burning mouth syndrome: A 1‐year follow‐up study.
- Authors
Paudel, Durga; Utsunomiya, Masafumi; Yoshida, Koki; Giri, Sarita; Uehara, Osamu; Matsuoka, Hirofumi; Chiba, Itsuo; Toyofuku, Akira; Abiko, Yoshihiro
- Abstract
Objective: Burning mouth syndrome (BMS) is a chronic intraoral burning sensation with no identifiable causes. In this study, we aim to demonstrate the effectiveness of treatment strategy using ethyl loflazepate monotherapy or in combination with milnacipran or amitriptyline. Method: A hospital‐based, retrospective study was conducted in 86 patients. The patients were divided into remission group and non‐remission group. The remission group comprised patients who were satisfied with their pain relief within a year of treatment initiation and did not require any follow‐up treatment. The treatment was considered effective if the patient got remission within 1 year or was able to reduce the visual analogue scale (VAS) score to <20, in the absence of remission. Results: The treatment strategy was effective in 76.7% of the patients. Significant reductions (p <.05) in VAS scores from 73.5 ± 14.2 at first visit to 14.7 ± 8.7 at last visit in the remission group, and from 79.7 ± 14.3 at first visit to 33.4 ± 23.7 after 1 year of treatment in the non‐remission group were noted. Conclusion: The treatment strategy using ethyl loflazepate monotherapy or in combination with milnacipran or amitriptyline can be very effective in reducing pain in BMS patients.
- Subjects
BENZODIAZEPINES; COMBINATION drug therapy; LONGITUDINAL method; PAIN; SEROTONIN uptake inhibitors; TRANQUILIZING drugs; PAIN management; PAIN measurement; VISUAL analog scale; TREATMENT effectiveness; DISEASE remission; RETROSPECTIVE studies; ADRENERGIC uptake inhibitors; AMITRIPTYLINE; BURNING mouth syndrome
- Publication
Oral Diseases, 2020, Vol 26, Issue 1, p193
- ISSN
1354-523X
- Publication type
Article
- DOI
10.1111/odi.13226