We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
SARS‐CoV‐2 screening for asymptomatic health care workers in UK stem cell transplant units.
- Authors
Bloor, Adrian J. C.; Dignan, Fiona L.; Lee, Julia; Orchard, Kim H.
- Abstract
SARS-CoV-2 screening for asymptomatic health care workers in UK stem cell transplant units Following the onset of the COVID-19 pandemic in early 2020, a range of risk factors have been identified underpinning the severity of infection observed in some patients following SARS-CoV-2 infection.1 These include obesity, advancing age, co-morbidities such as diabetes, hypertension and cardiovascular disease and more recent publications have also reported a significantly increased mortality in patients with underlying haematological malignancy.2 A greater risk may be anticipated in stem cell transplant recipients due to significant additional treatment-related immunosuppression although the magnitude of the additional risk from the transplant procedure I versus i that from the underlying diagnosis and patient-related factors is uncertain.3 A recent prospective study of the outcome for 272 HSCT recipients that tested positive for SARS-CoV-2 in European transplant centres reported a mortality rate of 30% and 25-3% for allogeneic and autologous HSCT recipients respectively,4 emphasising the high mortality risk to HSCT recipients from this virus. Testing was voluntary in most centres and focussed predominantly on patient-facing ward staff although practice between units varied considerably ranging from only sampling a limited number of staff, to routinely testing of all staff working in clinical areas.
- Subjects
UNITED Kingdom; MEDICAL personnel; STEM cell transplantation; SARS-CoV-2; UNIT cell; BONE marrow transplantation
- Publication
British Journal of Haematology, 2021, Vol 192, Issue 2, pe37
- ISSN
0007-1048
- Publication type
Article
- DOI
10.1111/bjh.17196