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- Title
Thrombospondin-1 and L-selectin are associated with silent cerebral infarct in children with sickle cell anaemia.
- Authors
Faulcon, Lisa M.; Fu, Zongming; Dulloor, Pratima; Barron‐Casella, Emily; Savage, William; Jennings, Jacky M.; Eyk, Jennifer E.; DeBaun, Michael; Casella, James F.; Everett, Allen
- Abstract
The article discusses the study on the relationship between thrombospondin-1 and L-selection with silent cerebral infarct in children with sickle cell anaemia. It states that baseline characteristics were similar between silent cerebral infraction (SCI) and non-SCI. It cites that patients with sickle cell anaemia (SCA) are at risk for increased inflammatory response. It also mentions that children with SCA are at risk of chronic and intermittent acute cerebral ischaemia events.
- Subjects
THROMBOSPONDIN-1; CEREBRAL infarction; SICKLE cell anemia; ISCHEMIA; INFLAMMATION
- Publication
British Journal of Haematology, 2013, Vol 162, Issue 3, p421
- ISSN
0007-1048
- Publication type
Article
- DOI
10.1111/bjh.12374