OpenURL Connection Search

Select item for more details and to access through your institution.

Neoadjuvant PD-1 blockade induces T cell and cDC1 activation but fails to overcome the immunosuppressive tumor associated macrophages in recurrent glioblastoma.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26940-2
By:
- Lee, Alexander H.;
- Sun, Lu;
- Mochizuki, Aaron Y.;
- Reynoso, Jeremy G.;
- Orpilla, Joey;
- Chow, Frances;
- Kienzler, Jenny C.;
- Everson, Richard G.;
- Nathanson, David A.;
- Bensinger, Steven J.;
- Liau, Linda M.;
- Cloughesy, Timothy;
- Hugo, Willy;
- Prins, Robert M.
Publication type:
Article
Resolution of tissue signatures of therapy response in patients with recurrent GBM treated with neoadjuvant anti-PD1.
Published in:
Nature Communications, 2021, v. 12, p. 1, doi. 10.1038/s41467-021-24293-4
By:
- Lu, Yue;
- Ng, Alphonsus H. C.;
- Chow, Frances E.;
- Everson, Richard G.;
- Helmink, Beth A.;
- Tetzlaff, Michael T.;
- Thakur, Rohit;
- Wargo, Jennifer A.;
- Cloughesy, Timothy F.;
- Prins, Robert M.;
- Heath, James R.
Publication type:
Article
Evidence for Innate and Adaptive Immune Responses in a Cohort of Intractable Pediatric Epilepsy Surgery Patients.
Published in:
Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00121
By:
- Owens, Geoffrey C.;
- Garcia, Alejandro J.;
- Mochizuki, Aaron Y.;
- Chang, Julia W.;
- Reyes, Samuel D.;
- Salamon, Noriko;
- Prins, Robert M.;
- Mathern, Gary W.;
- Fallah, Aria
Publication type:
Article
Author Correction: TLR agonists polarize interferon responses in conjunction with dendritic cell vaccination in malignant glioma: a randomized phase II Trial.
Published in:
2024
By:
- Everson, Richard G.;
- Hugo, Willy;
- Sun, Lu;
- Antonios, Joseph;
- Lee, Alexander;
- Ding, Lizhong;
- Bu, Melissa;
- Khattab, Sara;
- Chavez, Carolina;
- Billingslea-Yoon, Emma;
- Salazar, Andres;
- Ellingson, Benjamin M.;
- Cloughesy, Timothy F.;
- Liau, Linda M.;
- Prins, Robert M.
Publication type:
Correction Notice
TLR agonists polarize interferon responses in conjunction with dendritic cell vaccination in malignant glioma: a randomized phase II Trial.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48073-y
By:
- Everson, Richard G.;
- Hugo, Willy;
- Sun, Lu;
- Antonios, Joseph;
- Lee, Alexander;
- Ding, Lizhong;
- Bu, Melissa;
- Khattab, Sara;
- Chavez, Carolina;
- Billingslea-Yoon, Emma;
- Salazar, Andres;
- Ellingson, Benjamin M.;
- Cloughesy, Timothy F.;
- Liau, Linda M.;
- Prins, Robert M.
Publication type:
Article
Monitoring of Regulatory T Cell Frequencies and Expression of CTLA-4 on T Cells, before and after DC Vaccination, Can Predict Survival in GBM Patients.
Published in:
PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0032614
By:
- Fong, Brendan;
- Jin, Richard;
- Xiaoyan Wang;
- Safaee, Michael;
- Lisiero, Dominique N.;
- Yang, Isaac;
- Li, Gang;
- Liau, Linda M.;
- Prins, Robert M.
Publication type:
Article
Cover Image, Volume 36, Issue 6.
Published in:
2023
By:
- Cho, Nicholas S.;
- Hagiwara, Akifumi;
- Yao, Jingwen;
- Nathanson, David A.;
- Prins, Robert M.;
- Wang, Chencai;
- Raymond, Catalina;
- Desousa, Brandon R.;
- Divakaruni, Ajit;
- Morrow, Danielle H.;
- Nghiemphu, Phioanh L.;
- Lai, Albert;
- Liau, Linda M.;
- Everson, Richard G.;
- Salamon, Noriko;
- Pope, Whitney B.;
- Cloughesy, Timothy F.;
- Ellingson, Benjamin M.
Publication type:
Correction Notice
Amine‐weighted chemical exchange saturation transfer magnetic resonance imaging in brain tumors.
Published in:
NMR in Biomedicine, 2023, v. 36, n. 6, p. 1, doi. 10.1002/nbm.4785
By:
- Cho, Nicholas S.;
- Hagiwara, Akifumi;
- Yao, Jingwen;
- Nathanson, David A.;
- Prins, Robert M.;
- Wang, Chencai;
- Raymond, Catalina;
- Desousa, Brandon R.;
- Divakaruni, Ajit;
- Morrow, Danielle H.;
- Nghiemphu, Phioanh L.;
- Lai, Albert;
- Liau, Linda M.;
- Everson, Richard G.;
- Salamon, Noriko;
- Pope, Whitney B.;
- Cloughesy, Timothy F.;
- Ellingson, Benjamin M.
Publication type:
Article
Immunosensitization with a Bcl-2 small molecule inhibitor.
Published in:
Cancer Immunology, Immunotherapy, 2009, v. 58, n. 5, p. 699, doi. 10.1007/s00262-008-0592-4
By:
- Begley, Jonathan;
- Vo, Dan D.;
- Morris, Lilah F.;
- Bruhn, Kevin W.;
- Prins, Robert M.;
- Mok, Stephen;
- Koya, Richard C.;
- Garban, Hermes J.;
- Comin-Anduix, Begonya;
- Craft, Noah;
- Ribas, Antoni
Publication type:
Article
Anti-tumor activity and trafficking of self, tumor-specific T cells against tumors located in the brain.
Published in:
Cancer Immunology, Immunotherapy, 2008, v. 57, n. 9, p. 1279, doi. 10.1007/s00262-008-0461-1
By:
- Prins, Robert M.;
- Shu, Chengyi J.;
- Radu, Caius G.;
- Vo, Dan D.;
- Khan-Farooqi, Haumith;
- Soto, Horacio;
- Meng-Yin Yang;
- Muh-Shi Lin;
- Shelly, Stephanie;
- Witte, Owen N.;
- Ribas, Antoni;
- Liau, Linda M.
Publication type:
Article
Irradiated tumor cell vaccine for treatment of an established glioma. I. Successful treatment with combined radiotherapy and cellular vaccination.
Published in:
Cancer Immunology, Immunotherapy, 2002, v. 51, n. 4, p. 179, doi. 10.1007/s00262-002-0269-3
By:
- Graf, Martin R.;
- Prins, Robert M.;
- Hawkins, William T.;
- Merchant, Randall E.
Publication type:
Article
Irradiated tumor cell vaccine for treatment of an established glioma. II. Expansion of myeloid suppressor cells that promote tumor progression.
Published in:
Cancer Immunology, Immunotherapy, 2002, v. 51, n. 4, p. 190, doi. 10.1007/s00262-002-0270-x
By:
- Prins, Robert M.;
- Scott, Gail P.;
- Merchant, Randall E.;
- Graf, Martin R.
Publication type:
Article
Cytotoxic T cells infiltrating a glioma express an aberrant phenotype that is associated with decreased function and apoptosis.
Published in:
Cancer Immunology, Immunotherapy, 2001, v. 50, n. 6, p. 285, doi. 10.1007/s002620100202
By:
- Prins, Robert M.;
- Graf, Martin R.;
- Merchant, Randall E.
Publication type:
Article
Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities.
Published in:
Cancer & Metabolism, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40170-018-0177-4
By:
- Garrett, Matthew;
- Sperry, Jantzen;
- Braas, Daniel;
- Yan, Weihong;
- Le, Thuc M.;
- Mottahedeh, Jack;
- Ludwig, Kirsten;
- Eskin, Ascia;
- Qin, Yue;
- Levy, Rachelle;
- Breunig, Joshua J.;
- Pajonk, Frank;
- Graeber, Thomas G.;
- Radu, Caius G.;
- Christofk, Heather;
- Prins, Robert M.;
- Lai, Albert;
- Liau, Linda M.;
- Coppola, Giovanni;
- Kornblum, Harley I.
Publication type:
Article
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.
Published in:
Nature, 2010, v. 465, n. 7300, p. 966, doi. 10.1038/nature09132
By:
- Dang, Lenny;
- White, David W.;
- Gross, Stefan;
- Bennett, Bryson D.;
- Bittinger, Mark A.;
- Driggers, Edward M.;
- Fantin, Valeria R.;
- Jang, Hyun Gyung;
- Jin, Shengfang;
- Keenan, Marie C.;
- Marks, Kevin M.;
- Prins, Robert M.;
- Ward, Patrick S.;
- Yen, Katharine E.;
- Liau, Linda M.;
- Rabinowitz, Joshua D.;
- Cantley, Lewis C.;
- Thompson, Craig B.;
- Vander Heiden, Matthew G.;
- Su, Shinsan M.
Publication type:
Article
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.
Published in:
Nature, 2009, v. 462, n. 7274, p. 739, doi. 10.1038/nature08617
By:
- Dang, Lenny;
- White, David W.;
- Gross, Stefan;
- Bennett, Bryson D.;
- Bittinger, Mark A.;
- Driggers, Edward M.;
- Fantin, Valeria R.;
- Hyun Gyung Jang;
- Shengfang Jin;
- Keenan, Marie C.;
- Marks, Kevin M.;
- Prins, Robert M.;
- Ward, Patrick S.;
- Yen, Katharine E.;
- Liau, Linda M.;
- Rabinowitz, Joshua D.;
- Cantley, Lewis C.;
- Thompson, Craig B.;
- Vander Heiden, Matthew G.;
- Su, Shinsan M.
Publication type:
Article
Antigen presentation by clonally diverse CXCR5+ B cells to CD4 and CD8 T cells is associated with durable response to immune checkpoint inhibitors.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1176994
By:
- Lizhong Ding;
- Lu Sun;
- Bu, Melissa T.;
- Yanjun Zhang;
- Scott, Lauren N.;
- Prins, Robert M.;
- Su, Maureen A.;
- Lechner, Melissa G.;
- Hugo, Willy
Publication type:
Article
Emerging immunotherapies for malignant glioma: from immunogenomics to cell therapy.
Published in:
Neuro-Oncology, 2020, v. 22, n. 10, p. 1425, doi. 10.1093/neuonc/noaa154
By:
- Dunn, Gavin P;
- Cloughesy, Timothy F;
- Maus, Marcela V;
- Prins, Robert M;
- Reardon, David A;
- Sonabend, Adam M
Publication type:
Article
Metabolic characterization of human IDH mutant and wild type gliomas using simultaneous pH- and oxygen-sensitive molecular MRI.
Published in:
Neuro-Oncology, 2019, v. 21, n. 9, p. 1184, doi. 10.1093/neuonc/noz078
By:
- Yao, Jingwen;
- Chakhoyan, Ararat;
- Nathanson, David A;
- Yong, William H;
- Salamon, Noriko;
- Raymond, Catalina;
- Mareninov, Sergey;
- Lai, Albert;
- Nghiemphu, Phioanh L;
- Prins, Robert M;
- Pope, Whitney B;
- Everson, Richard G;
- Liau, Linda M;
- Cloughesy, Timothy F;
- Ellingson, Benjamin M
Publication type:
Article
Immunosuppressive tumor-infiltrating myeloid cells mediate adaptive immune resistance via a PD-1/PD-L1 mechanism in glioblastoma.
Published in:
Neuro-Oncology, 2017, v. 19, n. 6, p. 796, doi. 10.1093/neuonc/now287
By:
- Antonios, Joseph P.;
- Soto, Horacio;
- Everson, Richard G.;
- Moughon, Diana;
- Orpilla, Joey R.;
- Shin, Namjo P.;
- Sedighim, Shaina;
- Treger, Janet;
- Odesa, Sylvia;
- Tucker, Alexander;
- Yong, William H.;
- Gang Li;
- Cloughesy, Timothy F.;
- Liau, Linda M.;
- Prins, Robert M.
Publication type:
Article
Efficacy of systemic adoptive transfer immunotherapy targeting NY-ESO-1 for glioblastoma.
Published in:
Neuro-Oncology, 2016, v. 18, n. 3, p. 368, doi. 10.1093/neuonc/nov153
By:
- Everson, Richard G.;
- Antonios, Joseph P.;
- Lisiero, Dominique N.;
- Soto, Horacio;
- Scharnweber, Rudi;
- Garrett, Matthew C.;
- Yong, William H.;
- Ning Li;
- Gang Li;
- Kruse, Carol A.;
- Liau, Linda M.;
- Prins, Robert M.
Publication type:
Article
pH-weighted molecular imaging of gliomas using amine chemical exchange saturation transfer MRI.
Published in:
Neuro-Oncology, 2015, v. 17, n. 11, p. 1514, doi. 10.1093/neuonc/nov106
By:
- Harris, Robert J.;
- Cloughesy, Timothy F.;
- Liau, Linda M.;
- Prins, Robert M.;
- Antonios, Joseph P.;
- Debiao Li;
- Yong, William H.;
- Pope, Whitney B.;
- Lai, Albert;
- Nghiemphu, Phioanh L.;
- Ellingson, Benjamin M.
Publication type:
Article
CANCER IMMUNOTHERAPY AT THE CROSSROADS: HOW TUMORS EVADE IMMUNITY AND WHAT CAN BE DONE.
Published in:
2004
By:
- Prins, Robert M.;
- Liau, Linda M.
Publication type:
Book Review
Cellular and vaccine therapeutic approaches for gliomas.
Published in:
Journal of Translational Medicine, 2010, v. 8, p. 100, doi. 10.1186/1479-5876-8-100
By:
- Hickey, Michelle J.;
- Malone, Colin C.;
- Erickson, Kate L.;
- Jadus, Martin R.;
- Prins, Robert M.;
- Liau, Linda M.;
- Kruse, Carol A.
Publication type:
Article
Spatial immune profiling of glioblastoma identifies an inflammatory, perivascular phenotype associated with longer survival.
Published in:
Acta Neuropathologica, 2023, v. 146, n. 4, p. 647, doi. 10.1007/s00401-023-02617-6
By:
- Wirsching, Hans-Georg;
- Felsberg, Jörg;
- Prummer, Michael;
- Moisoiu, Vlad;
- Lourman, Roxanne;
- Hertler, Caroline;
- Antonios, Michelle;
- Cimino, Patrick J.;
- Roth, Patrick;
- Gorlia, Thierry;
- Prins, Robert M.;
- Cloughesy, Timothy;
- Wen, Patrick Y.;
- Holland, Eric C.;
- Reifenberger, Guido;
- Weller, Michael
Publication type:
Article
Lentiviral Vectors with CMV or MHCII Promoters Administered In Vivo: Immune Reactivity Versus Persistence of Expression.
Published in:
Molecular Therapy, 2007, v. 15, n. 7, p. 1390, doi. 10.1038/sj.mt.6300180
By:
- Kimura, Takahiro;
- Koya, Richard C.;
- Anselmi, Laura;
- Sternini, Catia;
- He-Jing Wang;
- Comin-Anduix, Begonya;
- Prins, Robert M.;
- Faure-Kumar, Emmanuelle;
- Rozengurt, Nora;
- Yan Cui;
- Kasahara, Noriyuki;
- Stripecke, Renata
Publication type:
Article
Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma.
Published in:
Signal Transduction & Targeted Therapy, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41392-023-01362-2
By:
- Hu, Junhui;
- Tan, Ping;
- Ishihara, Moe;
- Bayley, Nicholas A.;
- Schokrpur, Shiruyeh;
- Reynoso, Jeremy G.;
- Zhang, Yangjun;
- Lim, Raymond J.;
- Dumitras, Camelia;
- Yang, Lu;
- Dubinett, Steven M.;
- Jat, Parmjit S.;
- Van Snick, Jacques;
- Huang, Jiaoti;
- Chin, Arnold I.;
- Prins, Robert M.;
- Graeber, Thomas G.;
- Xu, Hua;
- Wu, Lily
Publication type:
Article
Validation of vessel size imaging (VSI) in high-grade human gliomas using magnetic resonance imaging, image-guided biopsies, and quantitative immunohistochemistry.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37564-w
By:
- Chakhoyan, Ararat;
- Yao, Jingwen;
- Leu, Kevin;
- Pope, Whitney B.;
- Salamon, Noriko;
- Yong, William;
- Lai, Albert;
- Nghiemphu, Phioanh L.;
- Everson, Richard G.;
- Prins, Robert M.;
- Liau, Linda M.;
- Nathanson, David A.;
- Cloughesy, Timothy F.;
- Ellingson, Benjamin M.
Publication type:
Article
IL-13Rα2/TGF-β bispecific CAR-T cells counter TGF-β-mediated immune suppression and potentiate anti-tumor responses in glioblastoma.
Published in:
Neuro-Oncology, 2024, v. 26, n. 10, p. 1850, doi. 10.1093/neuonc/noae126
By:
- Hou, Andrew J;
- Shih, Ryan M;
- Uy, Benjamin R;
- Shafer, Amanda;
- Chang, ZeNan L;
- Comin-Anduix, Begonya;
- Guemes, Miriam;
- Galic, Zoran;
- Phyu, Su;
- Okada, Hideho;
- Grausam, Katie B;
- Breunig, Joshua J;
- Brown, Christine E;
- Nathanson, David A;
- Prins, Robert M;
- Chen, Yvonne Y
Publication type:
Article
Commentary on "Dysfunctional dendritic cells limit antigen-specific T cell response in glioma".
Published in:
Neuro-Oncology, 2023, v. 25, n. 2, p. 277, doi. 10.1093/neuonc/noac256
By:
- Prins, Robert M;
- Everson, Richard G
Publication type:
Article
Diffusion MRI is an early biomarker of overall survival benefit in IDH wild-type recurrent glioblastoma treated with immune checkpoint inhibitors.
Published in:
Neuro-Oncology, 2022, v. 24, n. 6, p. 1020, doi. 10.1093/neuonc/noab276
By:
- Hagiwara, Akifumi;
- Oughourlian, Talia C;
- Cho, Nicholas S;
- Schlossman, Jacob;
- Wang, Chencai;
- Yao, Jingwen;
- Raymond, Catalina;
- Everson, Richard;
- Patel, Kunal;
- Mareninov, Sergey;
- Rodriguez, Fausto J;
- Salamon, Noriko;
- Pope, Whitney B;
- Nghiemphu, Phioanh L;
- Liau, Linda M;
- Prins, Robert M;
- Cloughesy, Timothy F;
- Ellingson, Benjamin M
Publication type:
Article
Author Correction: TLR agonists polarize interferon responses in conjunction with dendritic cell vaccination in malignant glioma: a randomized phase II Trial.
Published in:
2024
By:
- Everson, Richard G.;
- Hugo, Willy;
- Sun, Lu;
- Antonios, Joseph;
- Lee, Alexander;
- Ding, Lizhong;
- Bu, Melissa;
- Khattab, Sara;
- Chavez, Carolina;
- Billingslea-Yoon, Emma;
- Salazar, Andres;
- Ellingson, Benjamin M.;
- Cloughesy, Timothy F.;
- Liau, Linda M.;
- Prins, Robert M.
Publication type:
Correction Notice
Modulation of major histocompatibility complex Class I molecules and major histocompatibility complex-bound immunogenic peptides induced by interferon-a and interferon-? treatment of human glioblastoma multiforme.
Published in:
Journal of Neurosurgery, 2004, v. 100, n. 2, p. 310, doi. 10.3171/jns.2004.100.2.0310
By:
- Yang, Isaac;
- Kremen, Thomas J.;
- Giovannone, Adrian J.;
- Paik, Elena;
- Odesa, Sylvia K.;
- Prins, Robert M.;
- Liau, Linda M.
Publication type:
Article
Identification of Retinol Binding Protein 1 Promoter Hypermethylation in Isocitrate Dehydrogenase 1 and 2 Mutant Gliomas.
Published in:
JNCI: Journal of the National Cancer Institute, 2012, v. 104, n. 19, p. 1458, doi. 10.1093/jnci/djs357
By:
- Chou, Arthur P.;
- Chowdhury, Reshmi;
- Li, Sichen;
- Chen, Weidong;
- Kim, Andrew J.;
- Piccioni, David E.;
- Selfridge, Julia M.;
- Mody, Reema R.;
- Chang, Stephen;
- Lalezari, Shadi;
- Lin, Jeffrey;
- Sanchez, Desiree E.;
- Wilson, Ryan W.;
- Garrett, Matthew C.;
- Harry, Bret;
- Mottahedeh, Jack;
- Nghiemphu, Phioanh L.;
- Kornblum, Harley I.;
- Mischel, Paul S.;
- Prins, Robert M.
Publication type:
Article
EGFR Signaling Through an Akt-SREBP-1-Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Antilipogenic Therapy.
Published in:
Science Signaling, 2009, v. 2, n. 101, p. 1, doi. 10.1126/scisignal.2000446
By:
- Deliang Guo;
- Prins, Robert M.;
- Dang, Julie;
- Daisuke Kuga;
- Akio Iwanami;
- Soto, Horacio;
- Lin, Kelly Y.;
- Huang, Tiffany T.;
- Akhavan, David;
- Hock, M. Benjamin;
- Shaojun Zhu;
- Kofman, Ava A.;
- Bensinger, Steve J.;
- Yong, William H.;
- Vinters, Harry V.;
- Horvath, Steve;
- Watson, Andrew D.;
- Kuhn, John G.;
- Robins, H. Ian;
- Mehta, Minesh P.
Publication type:
Article

Found: 35