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- Title
HPV16 E6.
- Authors
Thomas, Karen J.; Smith, Kelly L.; Youde, Sarah J.; Evans, Mererid; Fiander, Alison N.; Borysiewicz, Leszek K.; Man, Stephen
- Abstract
Persistent human papillomavirus type 16 (HPV16) infection is associated with the development of more than 50% of cervical cancers. The HPV16 E6 and E7 oncoproteins are constitutively expressed in cervical carcinomas and are attractive targets for cytotoxic T lymphocyte (CTL)-based immunotherapy. However, cervical carcinomas may possess multiple evasion mechanisms for HPV16 E6/E7-specific CTL. In this study, we investigated whether HPV16
- Publication
International Journal of Cancer, 2008, Vol 122, Issue 12, p2791
- ISSN
0020-7136
- Publication type
Article
- DOI
10.1002/ijc.23475