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- Title
Event-related brain dynamics in ADHD.
- Authors
McLoughlin, Gráinne; Rijskdijk, Fruhling; Kuntsi, Jonna; Asherson, Philip; Bigdely Shamlo, Nima; Palmer, Jason; Makeig, Scott
- Abstract
Introduction and objective: Independent component analysis (ICA) (Delorme and Makeig 2004) exploits the temporal resolution of EEG to provide a richer characterisation of macroscopic neural differences associated with ADHD. In this study, we investigate the inter-trial variability in EEG indices of ADHD. Methods: 68 twin pairs were recruited from the Twins Early Development Study (TEDS). EEG data was recorded during the fast task (Andreou et al. 2007). Using ICA, neural event-related activity was identified in both conditions of the fast task. Results: We observed that activities of the component processes varied with time and conditions in several frequency bands. Discussion: The use of ICA can reveal the dynamics of brain source activation and synchronization phenomena in ADHD not revealed by standard scalp data averaging methods. The increased variability of these parameters in ADHD suggests that there is not an attentional deficit, per se, in ADHD but an inability to maintain consistent performance over time. Conclusion: These findings will aid in the characterisation of intraindividual variability in ADHD, both at the level of cortical processing and at the level of behavior.
- Publication
European Child & Adolescent Psychiatry, 2010, Vol 19, pS37
- ISSN
1018-8827
- Publication type
Article
- DOI
10.1007/s00787-010-0117-5