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- Title
Localizing the EGF receptor - Reply.
- Authors
Bourguignon, Lilly; Lan, Keng-hsueh; Singleton, Patrick; Lin, Shiaw-Yih; Yu, Dihua; Hung, Mien-Chie
- Abstract
Focuses on mechanisms involved in epidermal growth factor receptor (EGFR) nuclear localization. Occurrence of nuclear translocation of fibroblast growth factor receptor 1 via an importin-beta-dependent mechanism and possible involvement in transcriptional activity; Mutations in the transmembrane segment of HER-2/neu, a member of the EGFR family that changes a hydrophobic valine residue to a hydrophilic glutamic acid.
- Subjects
EPIDERMAL growth factor; CHROMOSOMAL translocation
- Publication
Nature Cell Biology, 2002, Vol 4, Issue 2, pE22
- ISSN
1465-7392
- Publication type
Article
- DOI
10.1038/ncb0202-e22b