We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
IMPLICAŢIILE STRESULUI OXIDATIV ÎN FIZIOLOGIA EFORTULUI FIZIC ÎN DISMETABOLISMUL POSTPRANDIAL INDUS EXPERIMENTAL.
- Authors
Chiş, Bogdan Augustin; Giurgea, Natalia; Daicoviciu, Doina; Mureșan, Adriana
- Abstract
Oxidative stress can be defined as a disruption of redox homeostasis or all the and oxidative damages as a result of an overproduction of reactive oxygen species or a reduction in the effectiveness of antioxidant sistems in the cell or whole organism, or both. Postprandial dismetabolism is an increasingly common problem in developed countries, and exercise is one of the most effective ways to combat obesity. The objective of the study was the evaluation of the metabolic changes caused by acute exercise on oxidant / antioxidant levels in postprandial dismetabolism. Material and methods. The experiment was performed on seven groups (n = 10 animals per group) of male Wistar rats, weighing 200±25g, which were determined parameters of oxidative stress: malondialdehyde as a parameter and prooxidant status and free SH groups as marker of antioxidant capacity in relation to exercise. Postprandial dismetabolism was simulated by intraperitoneal injection of 2 ml 33% glucose, respectively the administration of 2 ml of animal fat by feeding tube. Physical effort has been done using the treadmill. Statistical analysis was performed with the datas obtained from Mann-Whitney test and Spearman correlation index. Conclusions. Postprandial hyperglycemia and hyperlipaemia leads to increased oxidative stress. Acute postprandial exercise increases oxidative stress and reduces antoxidants levels that appears after a normal lunch, also in case of hyperglycemic or hyperlipemic lunches.
- Subjects
OXIDATIVE stress; QUALITATIVE research; ANTIOXIDANTS; MALONDIALDEHYDE
- Publication
Clujul Medical, 2011, Vol 84, Issue 2, p23
- ISSN
1222-2119
- Publication type
Case Study