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- Title
Baseline Demographic Profile and General Health Influencing the Post-Radiotherapy Health Related Quality-of-Life in Women with Gynaecological Malignancy Treated with Pelvic Irradiation.
- Authors
Sau, Sourav; Chatterjee, Shibram; Saha, Indranil; Sau, Saikat; Roy, Amitava
- Abstract
Background: Cancer specific survival and quality-of-life (QOL) assessment are important in evaluating cancer treatment outcomes. Baseline demographic profiles have significant effects on follow-up health related QOL (HRQOL) and affect the outcome of treatments. Materials and Methods: Post-operative gynaecological cancer patients required adjuvant pelvic radiation enrolled longitudinal assessment study. Patients had completed the short form-36 (SF-36) questionnaire before the adjuvant radiotherapy and functional assessments of cancer therapy-general module at 6th month's follow-up period to assess the HRQOL. Baseline variables were race, age, body mass index (BMI), education, marital status, type of surgery, physical composite scores (PCS) and mental composite scores (MCS) summary scores of the SF-36. Univariate and multivariate regression analysis used to determine the influence of these variables on post-radiotherapy HRQOL domains. Results: Baseline PCS, MCS, age, education and marital status had positively correlation with post-radiotherapy HRQOL while higher BMI had a negative impact in univariate analysis. In multivariate regression analysis, education and MCS had a positive correlation while higher BMI had a negative correlation with HRQOL domains. Conclusion: Enhance our ability to detect demographic variables and modify those factors and develops new treatment aimed at improving all aspect of gynaecological cancer including good QOL.
- Subjects
INDIA; STATISTICAL correlation; FEMALE reproductive organ tumors; HEALTH surveys; LONGITUDINAL method; SCIENTIFIC observation; PELVIC tumors; QUALITY of life; QUESTIONNAIRES; REGRESSION analysis; SURVIVAL; EDUCATIONAL attainment; BODY mass index; PRE-tests &; post-tests; PROPORTIONAL hazards models; DATA analysis software; DESCRIPTIVE statistics
- Publication
Indian Journal of Palliative Care, 2013, Vol 19, Issue 3, p186
- ISSN
0973-1075
- Publication type
Article
- DOI
10.4103/0973-1075.121540