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Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?
Published in:
Diabetologia, 2009, v. 52, n. 9, p. 1846, doi. 10.1007/s00125-009-1419-3
By:
- Southam, L.;
- Soranzo, N.;
- Montgomery, S.;
- Frayling, T.;
- McCarthy, M.;
- Barroso, I.;
- Zeggini, E.
Publication type:
Article
Common genetic variation in the melatonin receptor 1B gene ( MTNR1B) is associated with decreased early-phase insulin response.
Published in:
Diabetologia, 2009, v. 52, n. 8, p. 1537, doi. 10.1007/s00125-009-1392-x
By:
- Langenberg, C.;
- Pascoe, L.;
- Mari, A.;
- Tura, A.;
- Laakso, M.;
- Frayling, T.;
- Barroso, I.;
- Loos, R.;
- Wareham, N.;
- Walker, M.
Publication type:
Article
IRS2 variants and syndromes of severe insulin resistance.
Published in:
2009
By:
- Bottomley, W.;
- Soos, M.;
- Adams, C.;
- Guran, T.;
- Howlett, T.;
- Mackie, A.;
- Miell, J.;
- Monson, J.;
- Temple, R.;
- Tenenbaum-Rakover, Y.;
- Tymms, J.;
- Savage, D.;
- Semple, R.;
- O’Rahilly, S.;
- Barroso, I.
Publication type:
Letter
Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations.
Published in:
2008
By:
- Franks, P.;
- Rolandsson, O.;
- Debenham, S.;
- Fawcett, K.;
- Payne, F.;
- Dina, C.;
- Froguel, P.;
- Mohlke, K.;
- Willer, C.;
- Olsson, T.;
- Wareham, N.;
- Hallmans, G.;
- Barroso, I.;
- Sandhu, M.
Publication type:
Correction Notice
Testing of diabetes-associated WFS1 polymorphisms in the Diabetes Prevention Program.
Published in:
Diabetologia, 2008, v. 51, n. 3, p. 451, doi. 10.1007/s00125-007-0891-x
By:
- Florez, J.;
- Jablonski, K.;
- McAteer, J.;
- Sandhu, M.;
- Wareham, N.;
- Barroso, I.;
- Franks, P.;
- Altshuler, D.;
- Knowler, W.
Publication type:
Article
Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations.
Published in:
Diabetologia, 2008, v. 51, n. 3, p. 458, doi. 10.1007/s00125-007-0887-6
By:
- Franks, P.;
- Rolandsson, O.;
- Debenham, S.;
- Fawcett, K.;
- Payne, F.;
- Dina, C.;
- Froguel, P.;
- Mohlke, K.;
- Willer, C.;
- Olsson, T.;
- Wareham, N.;
- Hallmans, G.;
- Barroso, I.;
- Sandhu, M.
Publication type:
Article
Mendelian randomisation studies of type 2 diabetes: future prospects.
Published in:
Diabetologia, 2008, v. 51, n. 2, p. 211, doi. 10.1007/s00125-007-0903-x
By:
- Sandhu, M.;
- Debenham, S.;
- Barroso, I.;
- Loos, R.
Publication type:
Article
PPARGC1A coding variation may initiate impaired NEFA clearance during glucose challenge.
Published in:
Diabetologia, 2007, v. 50, n. 3, p. 569, doi. 10.1007/s00125-006-0580-1
By:
- Franks, P.;
- Ekelund, U.;
- Brage, S.;
- Luan, J.;
- Schafer, A.;
- O’Rahilly, S.;
- Barroso, I.;
- Wareham, N.
Publication type:
Article
Adiponectin receptor genes: mutation screening in syndromes of insulin resistance and association studies for type 2 diabetes and metabolic traits in UK populations.
Published in:
Diabetologia, 2007, v. 50, n. 3, p. 555, doi. 10.1007/s00125-006-0534-7
By:
- Collins, S.;
- Luan, J.;
- Thompson, A.;
- Daly, A.;
- Semple, R.;
- O’Rahilly, S.;
- Wareham, N.;
- Barroso, I.
Publication type:
Article
Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes.
Published in:
Diabetologia, 2006, v. 49, n. 3, p. 501, doi. 10.1007/s00125-005-0130-2
By:
- Barroso, I.;
- Luan, J.;
- Sandhu, M. S.;
- Franks, P. W.;
- Crowley, V.;
- Schafer, A. J.;
- O'Rahilly, S.;
- Wareham, N. J.
Publication type:
Article
Familial partial lipodystrophy associated with compound heterozygosity for novel mutations in the LMNAgene.
Published in:
2004
By:
- McFarlane, I.;
- Halsall, D. J.;
- Barroso, I.;
- Thomas, E. L.;
- Bell, J. D.;
- Scobie, I.;
- Belchetz, P. E.;
- Kelly, W. F.;
- Schafer Incyte, A. J.
Publication type:
Letter
Whole-genome association study of antibody response to Epstein-Barr virus in an African population: A pilot.
Published in:
Global Health, Epidemiology & Genomics, 2017, v. 2, p. 1, doi. 10.1017/gheg.2017.16
By:
- Sallah, N.;
- Carstensen, T.;
- Wakeham, K.;
- Bagni, R.;
- Labo, N.;
- Pollard, M. O.;
- Gurdasani, D.;
- Ekoru, K.;
- Pomilla, C.;
- Young, E. H.;
- Fatumo, S.;
- Asiki, G.;
- Kamali, A.;
- Sandhu, M.;
- Kellam, P.;
- Whitby, D.;
- Barroso, I.;
- Newton, R.
Publication type:
Article
The flashfm approach for fine-mapping multiple quantitative traits.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26364-y
By:
- Hernández, N.;
- Soenksen, J.;
- Newcombe, P.;
- Sandhu, M.;
- Barroso, I.;
- Wallace, C.;
- Asimit, J. L.
Publication type:
Article
The human nucleoporin Tpr protects cells from RNA-mediated replication stress.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24224-3
By:
- Kosar, Martin;
- Giannattasio, Michele;
- Piccini, Daniele;
- Maya-Mendoza, Apolinar;
- García-Benítez, Francisco;
- Bartkova, Jirina;
- Barroso, Sonia I.;
- Gaillard, Hélène;
- Martini, Emanuele;
- Restuccia, Umberto;
- Ramirez-Otero, Miguel Angel;
- Garre, Massimiliano;
- Verga, Eleonora;
- Andújar-Sánchez, Miguel;
- Maynard, Scott;
- Hodny, Zdenek;
- Costanzo, Vincenzo;
- Kumar, Amit;
- Bachi, Angela;
- Aguilera, Andrés
Publication type:
Article
Investigação sobre a satisfação e os efeitos de móveis utilizados por estudantes universitários.
Published in:
Journal of Occupational Therapy of University of São Paulo / Revista de Terapia Ocupacional da Universidade de São Paulo, 2014, v. 25, n. 3, p. 289, doi. 10.11606/issn.2238-6149.v25i3p289-298
By:
- de Souza, Marina Batista Chaves Azevedo;
- Marcolino, Alisson Vieira;
- do Nascimento, Rívia Lopes;
- de Oliveira, Eliza R.;
- de Souza, Erivaldo L.;
- de L. Barroso, Bárbara I.
Publication type:
Article
P15 Children's health literacy in school – a scooping review.
Published in:
2019
By:
- Vieira, M;
- Reis, A;
- Barroso, I
Publication type:
Abstract
O34 The needs expressed by adolescents about health literacy on the web platform "Your PEL".
Published in:
2019
By:
- Guia, P;
- Spínola, A;
- Barroso, I;
- Dias, H
Publication type:
Abstract
O18 Development of help and surveillance technologies for dependent elderly people at home.
Published in:
2019
By:
- Rodrigues, V;
- Monteiro, M J;
- Soares, S;
- Valente, A;
- Silva, S;
- Sousa, M;
- Duarte, D;
- Rainho, C;
- Barroso, I
Publication type:
Abstract
Erratum: Digenic inheritance of severe insulin resistance in a human pedigree.
Published in:
2002
By:
- Savage, D B;
- Agostini, M;
- Barroso, I;
- Gurnell, M;
- Luan, J;
- Meirhaeghe, A;
- Harding, A-H;
- Ihrke, G;
- Rajanayagam, O;
- Soos, M A;
- George, S;
- Berger, D;
- Thomas, E L;
- Bell, J D;
- Meeran, K;
- Ross, R J;
- Vidal-Puig, A;
- Wareham, N J;
- O'Rahilly, S
Publication type:
Correction Notice
Atrial matrix remodeling in atrial fibrillation patients with aortic stenosis.
Published in:
2020
By:
- Fragão-Marques, Mariana;
- Miranda, I.;
- Martins, D.;
- Barroso, I.;
- Mendes, C.;
- Pereira-Neves, A.;
- Falcão-Pires, I.;
- Leite-Moreira, A.
Publication type:
journal article
Founder effect in the Horn of Africa for an insulin receptor mutation that may impair receptor recycling.
Published in:
Diabetologia, 2011, v. 54, n. 5, p. 1057, doi. 10.1007/s00125-011-2066-z
By:
- Raffan, E.;
- Soos, M.;
- Rocha, N.;
- Tuthill, A.;
- Thomsen, A.;
- Hyden, C.;
- Gregory, J.;
- Hindmarsh, P.;
- Dattani, M.;
- Cochran, E.;
- Kaabi, J.;
- Gorden, P.;
- Barroso, I.;
- Morling, N.;
- O'Rahilly, S.;
- Semple, R.
Publication type:
Article
Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population.
Published in:
Diabetologia, 2010, v. 53, n. 10, p. 2155, doi. 10.1007/s00125-010-1792-y
By:
- Fontaine-Bisson, B.;
- Renström, F.;
- Rolandsson, O.;
- Payne, F.;
- Hallmans, G.;
- Barroso, I.;
- Franks, P.
Publication type:
Article
Analysis of TBC1D4 in patients with severe insulin resistance.
Published in:
2010
By:
- Dash, S.;
- Langenberg, C.;
- Fawcett, K.;
- Semple, R.;
- Romeo, S.;
- Sharp, S.;
- Sano, H.;
- Lienhard, G.;
- Rochford, J.;
- Howlett, T.;
- Massoud, A.;
- Hindmarsh, P.;
- Howell, S.;
- Wilkinson, R.;
- Lyssenko, V.;
- Groop, L.;
- Baroni, M.;
- Barroso, I.;
- Wareham, N.;
- O’ Rahilly, S.
Publication type:
Letter
Genetics of Type 2 diabetes.
Published in:
2005
By:
- Barroso I
Publication type:
Journal Article
Genetics of Type 2 diabetes.
Published in:
Diabetic Medicine, 2005, v. 22, n. 5, p. 517, doi. 10.1111/j.1464-5491.2005.01550.x
By:
- Barroso, I.
Publication type:
Article
Genetic variants of insulin receptor substrate-1 (IRS-1) in syndromes of severe insulin resistance. Functional analysis of Ala513Pro and Gly1158Glu IRS-1.
Published in:
Diabetic Medicine, 2002, v. 19, n. 10, p. 804, doi. 10.1046/j.1464-5491.2002.00779.x
By:
- Berger, D.;
- Barroso, I.;
- Soos, M.;
- Yeo, G.;
- Schafer, A. J.;
- O'Rahilly, S.;
- Whitehead, J. P.
Publication type:
Article
TDP-43 mutations link Amyotrophic Lateral Sclerosis with R-loop homeostasis and R loop-mediated DNA damage.
Published in:
PLoS Genetics, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pgen.1009260
By:
- Gianini, Marta;
- Bayona-Feliu, Aleix;
- Sproviero, Daisy;
- Barroso, Sonia I.;
- Cereda, Cristina;
- Aguilera, Andrés
Publication type:
Article
Influence of fraxetin on the lifespan and longevity facing induced stress.
Published in:
Phytotherapy Research, 1998, v. 12, n. S1, p. S107, doi. 10.1002/(SICI)1099-1573(1998)12:1+<S107::AID-PTR266>3.0.CO;2-C
By:
- Dolz, I. Barroso;
- Fernández-Puntero, B.;
- Benedí, J.;
- Iglesias, I.;
- del Fresno, A. Villar
Publication type:
Article
Loss of NPC1 function in a patient with a co‐inherited novel insulin receptor mutation does not grossly modify the severity of the associated insulin resistance.
Published in:
Journal of Inherited Metabolic Disease, 2010, v. 33, p. 227, doi. 10.1007/s10545-010-9107-5
By:
- Kirk, J.;
- Porter, K. M.;
- Parker, V.;
- Barroso, I.;
- O'Rahilly, S.;
- Hendriksz, C.;
- Semple, R. K.
Publication type:
Article
Loss of NPC1 function in a patient with a co-inherited novel insulin receptor mutation does not grossly modify the severity of the associated insulin resistance.
Published in:
Journal of Inherited Metabolic Disease, 2010, v. 33, p. S227, doi. 10.1007/s10545-010-9107-5
By:
- Kirk, J.;
- Porter, K. M.;
- Parker, V.;
- Barroso, I.;
- O'Rahilly, S.;
- Hendriksz, C.;
- Semple, R. K.
Publication type:
Article
Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies.
Published in:
2008
By:
- Barroso I;
- Luan J;
- Wheeler E;
- Whittaker P;
- Wasson J;
- Zeggini E;
- Weedon MN;
- Hunt S;
- Venkatesh R;
- Frayling TM;
- Delgado M;
- Neuman RJ;
- Zhao J;
- Sherva R;
- Glaser B;
- Walker M;
- Hitman G;
- McCarthy MI;
- Hattersley AT;
- Permutt MA
Publication type:
journal article
TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population.
Published in:
2007
By:
- Loos RJ;
- Franks PW;
- Francis RW;
- Barroso I;
- Gribble FM;
- Savage DB;
- Ong KK;
- O'Rahilly S;
- Wareham NJ;
- Loos, Ruth J F;
- Franks, Paul W;
- Francis, Richard W;
- Barroso, Inês;
- Gribble, Fiona M;
- Savage, David B;
- Ong, Ken K;
- O'Rahilly, Stephen;
- Wareham, Nicholas J
Publication type:
journal article
Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies.
Published in:
2007
By:
- Mesa JL;
- Loos RJ;
- Franks PW;
- Ong KK;
- Luan J;
- O'rahilly S;
- Wareham NJ;
- Barroso I;
- Mesa, José L;
- Loos, Ruth J F;
- Franks, Paul W;
- Ong, Ken K;
- Luan, Jian'an;
- O'Rahilly, Stephen;
- Wareham, Nicholas J;
- Barroso, Inês
Publication type:
journal article
Analysis of genetic variation in Akt2/PKB-beta in severe insulin resistance, lipodystrophy, type 2 diabetes, and related metabolic phenotypes.
Published in:
2007
By:
- Tan K;
- Kimber WA;
- Luan J;
- Soos MA;
- Semple RK;
- Wareham NJ;
- O'rahilly S;
- Barroso I;
- Tan, Karen;
- Kimber, Wendy A;
- Luan, Jian'an;
- Soos, Maria A;
- Semple, Robert K;
- Wareham, Nicholas J;
- O'Rahilly, Stephen;
- Barroso, Inês
Publication type:
journal article
BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2.
Published in:
Nature, 2014, v. 511, n. 7509, p. 362, doi. 10.1038/nature13374
By:
- Bhatia, Vaibhav;
- Barroso, Sonia I.;
- García-Rubio, María L.;
- Tumini, Emanuela;
- Herrera-Moyano, Emilia;
- Aguilera, Andrés
Publication type:
Article
Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02756-x
By:
- Duch, Alba;
- Canal, Berta;
- Barroso, Sonia I.;
- García-Rubio, María;
- Seisenbacher, Gerhard;
- Aguilera, Andrés;
- de Nadal, Eulàlia;
- Posas, Francesc
Publication type:
Article
The Fanconi Anemia Pathway Protects Genome Integrity from R-loops.
Published in:
PLoS Genetics, 2015, v. 11, n. 11, p. 1, doi. 10.1371/journal.pgen.1005674
By:
- García-Rubio, María L.;
- Pérez-Calero, Carmen;
- Barroso, Sonia I.;
- Tumini, Emanuela;
- Herrera-Moyano, Emilia;
- Rosado, Iván V.;
- Aguilera, Andrés
Publication type:
Article
Steady state fluorescence to study nanocomposites based on silica nanoparticles and thermoplastic polymer matrices.
Published in:
Polymer Composites, 2011, v. 32, n. 11, p. 1874, doi. 10.1002/pc.21199
By:
- Barroso, I.;
- González-Benito, J.
Publication type:
Article
DIEZ AÑOS DE FUNCIONAMIENTO DE LA RED NACIONAL DE VIGILANCIA RADIOLÓGICA AMBIENTAL EN LA REPÚBLICA DE CUBA.
Published in:
Nucleus, 2000, n. 28, p. 32
By:
- Alvarado, J. A. Corcho;
- Alonso, M. Prendes;
- Zerquera, J. Tom´s;
- Sed, L. Jova;
- Hernández, C. Alonso;
- Brígido, O.;
- Barroso, I.;
- Sánchez, D. Pérez;
- Leyva, J. C.
Publication type:
Article
METODO PARA EL CONTROL DE LOS NIVELES DE ACTIVIDAD EN AIRE POR LA PRESENCIA DE AEROSOLES RADIACTIVOS.
Published in:
Nucleus, 1995, n. 19, p. 16
By:
- Díaz, N. Cornejo;
- Jiménez, M. T. Alonso;
- Zerquera, J. Tomás;
- Pérez, I. Barroso
Publication type:
Article
Impact of Bariatric Surgery on Long-term Cardiovascular Risk: Comparative Effectiveness of Different Surgical Procedures.
Published in:
Obesity Surgery, 2020, v. 30, n. 2, p. 673, doi. 10.1007/s11695-019-04237-0
By:
- Oliveira, Sofia Castro;
- Neves, J. S.;
- Souteiro, P.;
- Pedro, J.;
- Magalhães, D.;
- Guerreiro, V.;
- Bettencourt-Silva, R.;
- Costa, M. M.;
- Varela, A.;
- Barroso, I.;
- Freitas, P.;
- Carvalho, D.
Publication type:
Article
Dominant negative mutations in human PPAR gamma associated with severe insulin resistance...
Published in:
Nature, 1999, v. 402, n. 6764, p. 880, doi. 10.1038/47254
By:
- Barroso, I.;
- Gurnell, M.
Publication type:
Article
The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals.
Published in:
2007
By:
- Young, E. H.;
- Wareham, N. J.;
- Farooqi, S.;
- Hinney, A.;
- Hebebrand, J.;
- Scherag, A.;
- O'Rahilly, S.;
- Barroso, I.;
- Sandhu, M. S.
Publication type:
journal article

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