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- Title
Severe Food Protein‐Induced Enterocolitis Syndrome After Hematopoietic Stem Cell Transplantation: Pediatric Case Report.
- Authors
Alonso García, Laura; Romero, Melissa Panesso; Macías, Elena García; Cantón, Oscar Segarra; Rubio, Cristina Diaz de Heredia
- Abstract
Background: Food protein‐induced enterocolitis syndrome (FPIES) is a non–IgE‐mediated food allergy. In the last few years, after the publication of the consensus guidelines, with refined diagnostic criteria and improved awareness, FPIES is diagnosed with increased frequency. However, despite having a background of immune dysregulation, this complication has just been described once in the posttransplant setting, in an adult patient. To the best of our knowledge, there are no reports of pediatric patients developing FPIES after a hematopoietic stem cell transplant (HCT). Methods: Retrospective review of a pediatric patient who developed severe FPIEs after a HCT. Results: In this case report, the clinical presentation and diagnosis challenges of a pediatric patient who developed severe FPIES after HCT are described. The patient developed severe vomiting, diarrhea, lethargy, and shock and required admission to the pediatric intensive care unit in three occasions before the diagnosis was made. Conclusions: To the best of our knowledge, this is the first report of severe FPIES post‐HCT in a pediatric patient. Physicians who are looking after pediatric patients in the post‐HCT setting need to be aware of this possibility and include this entity in the differential diagnosis in order to reduce its associated morbidity.
- Subjects
HEMATOPOIETIC stem cell transplantation; ENTEROCOLITIS; CHILD patients; STEM cell transplantation; HEMATOPOIETIC stem cells; MILK allergy
- Publication
Pediatric Transplantation, 2024, Vol 28, Issue 5, p1
- ISSN
1397-3142
- Publication type
Article
- DOI
10.1111/petr.14810