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- Title
Hastanede yatan hastaların klinik örneklerinden izole edilen enterokok suşlarının antibiyotik duyarlılıklarının değerlendirilmesi.
- Authors
ÖDEMIŞ, İlker; KÖSE, Şükran; ERSAN, Gürsel; ÇELIK, Didem; AKBULUT, İlkay
- Abstract
Objective: Enterococci can cause urinary tract infection, wound infection and bacteremia. It is one of the most commonly detected agents in hospitalacquired infections. Increasing resistance to antibiotics has been observed in enterococci in recent years. The distribution of enterococci isolated from cultures and antibiotic resistance may vary between health care centers, so it would be beneficial for each center to evaluate its own results at certain intervals. The aim of this study is to determine the antibiotic resistance rates of Enterococcus faecalis and Enterococcus faecium strains isolated from urine, blood, wound, sputum and cerebrospinal fluid (CSF) specimens of patients hospitalized in our hospital, such as ampicillin, gentamicin, streptomycin, ciprofloxacin, vancomycin, teicoplanin and linezolid. Methods: Between January 2010 and January 2015, 390 Enterococcus strains isolated from various clinical specimens of patients in İzmir Tepecik Training and Research Hospital were evaluated retrospectively. Identification and antibiotic susceptibility testing of the enterococci strains were performed by fully automated bacterial identification system VITEK-2 (bioMerieux, France). Vancomycin, teicoplanin and linezolid resistance was also tested by the E-test method (bioMerieux, Fransa). Susceptibility results were evaluated according to the guidelines of Clinical and Laboratory Standards Institute (CLSI). Results: A total of 390 strains were identified as follows; 154 (%40) were E. faecalis, 236 (%60) were E. faecium. Clinical specimens from which E. faecium strains were isolated were; 126 (53%) urine, 65 (27%) blood, 39 (17%) wound, 4 (2%) sputum and 2 (1%) CSF. Clinical specimens from which E. faecalis strains were isolated were; 77 (50%) urine, 50 (33%) blood, 22 (14%) wound, 3 (2%) sputum and 2 (1%) CSF. Linezolid was the most sensitive antibiotic against both E. faecalis and E. faecium strains, Ampicillin was the most resistant antibiotic for both E. faecalis and E. faecium strains. Conclusion: In our study; the detection of high ampicillin, vancomycin and teicoplanin resistance in both E. faecalis and E. faecium strains is considered to be a data that should be taken into consideration in the selection of empirical antibiotics for these strains.
- Publication
Turkish Bulletin of Hygiene & Experimental Biology / Türk Hijyen ve Deneysel Biyoloji, 2018, Vol 75, Issue 4, p345
- ISSN
0377-9777
- Publication type
Article
- DOI
10.5505/TurkHijyen.2018.70456