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- Title
Association between Cyclooxygenase-2 and Matrix Metalloproteinase-2 Expression in Non-Small Cell Lung Cancer.
- Authors
Byun, Jae Ho; Lee, Myung Ah; Roh, Sang Young; Shim, Byoung Yong; Hong, Sook Hee; Ko, Yoon Ho; Ko, Su Jin; Woo, In Sook; Kang, Jin Hyoung; Hong, Young Seon; Lee, Kyung Shik; Lee, Ah Won; Park, Gyeong Sin; Lee, Kyo Yeong
- Abstract
Background: Cyclooxygenase-2 (COX-2) contributes to invasiveness of cancer through activation of several matrix metalloproteinases (MMPs). Matrix metalloproteinase-2 (MMP-2) is a proteolytic enzyme that degrades the extracellular matrix, and has been linked to invasion and metastasis. This study aims to assess the correlation of the COX-2 expression and the MMP-2 expression in patients with non-small cell lung cancer (NSCLC).
- Publication
Japanese Journal of Clinical Oncology, 2006, Vol 36, Issue 5, p263
- ISSN
0368-2811
- Publication type
Article
- DOI
10.1093/jjco/hyl024