We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Proteome analysis of lumbar spinal cord from rats submitted to peripheral lesion during neonatal period.
- Authors
Castro-Dias, Erich; Vieira, André S.; Werneck, Claudio C.; Langone, Francesco; Novello, José C.; Martins-de-Souza, Daniel
- Abstract
Every year traumatic peripheral nerve injuries (TPNI) result in considerable physical disability across the world; the mechanisms of plasticity and reorganization of spinal cord circuits following such injuries are complex and not completely understood. A comparative proteome analysis between neonatal rats submitted to peripheral lesion and controls was performed; a number of differentially expressed proteins involved in oxidative stress response, energy metabolism and cytoskeleton rearrangement were revealed, which may support future studies to help in the understanding and a posteriori the treatment of TPNI.
- Subjects
SPINAL cord injuries; LUMBAR vertebrae; METABOLISM; PERIPHERAL nervous system; OXIDATIVE stress
- Publication
Journal of Neural Transmission, 2010, Vol 117, Issue 6, p689
- ISSN
0300-9564
- Publication type
Article
- DOI
10.1007/s00702-010-0403-x