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- Title
Chemical composition and antioxidant activity of Astragalus monspessulanus L. growing in semiarid areas of Algeria.
- Authors
BOUREZZANE, SAWSEN; HABA, HAMADA; CHRISTOPHE LONG; BENKHALED, MOHAMMED
- Abstract
This paper reports a phytochemical study of the aerial parts of Astragalus monspessulanus L. growing in Algeria. It deals with the isolation and structure elucidation of 13 known compounds. From the n-butanol extract, seven flavonoids 1-7, two saponins and one lignan were isolated. In addition, two phytosterols and one triterpenoid were isolated from the ethyl acetate extract. Structures of all the isolated products were determined by using 1D and 2D-NMR techniques, measurement of optical rotation, mass spectrometry ESIMS and by comparison with literature data. Furthermore, the antioxidant activity of the n-butanol extract of the aerial parts of Astragalus monspessulanus L. was investigated using the DPPH radical scavenging and ferrous ion chelating assays. The n-butanol extract showed low (EC50 = 2.0876 ± 0.4363 mg/mL) to moderate (IC50 = 63.60 ± 0.01436 μg/mL) antioxidant activities depending on the tested method.
- Subjects
ALGERIA; SAPONINS in agriculture; ARID regions; ANTIOXIDANTS; MASS spectrometry
- Publication
Journal of the Serbian Chemical Society, 2018, Vol 83, Issue 1, p1
- ISSN
0352-5139
- Publication type
Article
- DOI
10.2298/JSC161212085B