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- Title
NBC: the Naïve Bayes Classification tool webserver for taxonomic classification of metagenomic reads.
- Authors
Rosen, Gail L.; Reichenberger, Erin R.; Rosenfeld, Aaron M.
- Abstract
Motivation: Datasets from high-throughput sequencing technologies have yielded a vast amount of data about organisms in environmental samples. Yet, it is still a challenge to assess the exact organism content in these samples because the task of taxonomic classification is too computationally complex to annotate all reads in a dataset. An easy-to-use webserver is needed to process these reads. While many methods exist, only a few are publicly available on webservers, and out of those, most do not annotate all reads.Results: We introduce a webserver that implements the naïve Bayes classifier (NBC) to classify all metagenomic reads to their best taxonomic match. Results indicate that NBC can assign next-generation sequencing reads to their taxonomic classification and can find significant populations of genera that other classifiers may miss.Availability: Publicly available at: http://nbc.ece.drexel.edu.Contact: gailr@ece.drexel.edu
- Subjects
INTERNET servers; BIOLOGICAL classification; METADATA; COMPUTATIONAL complexity; GENOMICS; MATHEMATICAL sequences
- Publication
Bioinformatics, 2011, Vol 27, Issue 1, p127
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/btq619