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- Title
De novo transcriptome assembly with ABySS.
- Authors
Birol, Inanç; Jackman, Shaun D.; Nielsen, Cydney B.; Qian, Jenny Q.; Varhol, Richard; Stazyk, Greg; Morin, Ryan D.; Zhao, Yongjun; Hirst, Martin; Schein, Jacqueline E.; Horsman, Doug E.; Connors, Joseph M.; Gascoyne, Randy D.; Marra, Marco A.; Jones, Steven J. M.
- Abstract
Motivation: Whole transcriptome shotgun sequencing data from non-normalized samples offer unique opportunities to study the metabolic states of organisms. One can deduce gene expression levels using sequence coverage as a surrogate, identify coding changes or discover novel isoforms or transcripts. Especially for discovery of novel events, de novo assembly of transcriptomes is desirable.
- Subjects
GENE expression; GENETIC regulation; GENETIC transcription; LYMPHOMAS; BIOINFORMATICS
- Publication
Bioinformatics, 2009, Vol 25, Issue 21, p2872
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/btp367