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- Title
Hastanemize Başvuran Gebe Hastalarda Rubella, Cytomegalovırus, Toxoplasma Gondii Seroprevalansı, Ölü Doğum ve Erken Doğum Oranları, Igg Pozitif Hastalarda Igg Avidite Karşılaştırılması.
- Authors
Gürbüz, Esra; Baran, Ali Irfan
- Abstract
The aim of this study is to identify seroprevalence of Rubella, Cytomegalovirus and T. gondii in pregnancies, determination of stillbirth and preterm delivery rates and comparison of IgG avidity with avidity in pregnant patients with positive IgG antibodies. The study was carried out by ELISA method in order to investigate Cytomegalovirus, Rubella and T.gondii IgG and IgM antibodies in 300 blood samples taken from pregnant patients between the ages of 18-48 who applied to the Gynecology and Obstetrics Outpatient Clinic. Rubella IgG 96% and Rubella IgM 4%, CMV IgG 99%, CMV IgM 1.3%, T. gondii IgG 56.3% and IgM 7.6% seropositivity were detected in pregnant blood samples. In the blood samples taken in pregnant women with stillbirth / preterm birth, the rates were Rubella IgM 2 (18.1%) / 4 (17.3%), Rubella IgG 11 (100%) / 22 (95.6%), CMV IgM 1 (9%) / 2 (8.6%), CMV IgG 11 (100%) / 23 (100%), T.gondii IgM 1 (9%) / 3 (13%), T.gondiiIgG 4 (36%, 3) / 8 (34.7%). The avidity values were determined as 3/0/2 in Rubella, 0/0/3 in Cytomegalovirus and 8/1/12 in T. gondii in low / gray zone / high values respectively. As a result, Toxoplasma gondii, Cytomegalovirus and Rubella, which may cause aborts or stillbirths, are among the important health problems in pregnant patients in our region. It has been concluded that serologic methods may be a method of guiding medicine in diagnosing these infections and clarifying suspicious cases by performing IgG avidity test.
- Publication
Van Tip Dergisi, 2021, Vol 28, Issue 2, p300
- ISSN
1300-2694
- Publication type
Article
- DOI
10.5505/vtd.2021.54036