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- Title
Non-invasive determination of the paternal HLA haplotype of a fetus using kinetic PCR to detect fetal microchimerism in maternal plasma.
- Authors
Reed, W.; Kong, D. Z.; Lee, T-H.; Cowan, M. J.; Busch, M. P.; Baxter-Lowe, L. A.
- Abstract
Presents a case study of non-invasive determination of paternally inherited fetal HLA haplotype and the use of kinetic polymerase chain reaction to detect fetal DNA in maternal plasma during the third semester of pregnancy. Example of HLA haplotype for each parent and other possible combinations of paternal and maternal haplotype; Problems encountered in the enrichment of fetal cells from maternal blood; Limitations of the study.
- Subjects
POLYMERASE chain reaction; FETAL cells from maternal blood
- Publication
Bone Marrow Transplantation, 2002, Vol 29, Issue 6, p527
- ISSN
0268-3369
- Publication type
Case Study
- DOI
10.1038/sj.bmt.1703411