We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
The translational gap for gene therapies in low- and middle-income countries.
- Authors
Doxzen, Kevin W.; Adair, Jennifer E.; Fonseca Bazzo, Yris Maria; Bukini, Daima; Cornetta, Kenneth; Dalal, Varsha; Guerino-Cunha, Renato Luiz; Hongeng, Suradej; Jotwani, Geeta; Kityo-Mutuluuza, Cissy; Lakshmanan, Krishnamurti; Mahlangu, Johnny; Makani, Julie; Mathews, Vikram; Ozelo, Margareth C.; Rangarajan, Savita; Scholefield, Janine; Batista Silva Júnior, João; McCune, Joseph M.
- Abstract
Gene therapies are designed to address the root cause of disease. As scientific understanding of disease prevention, diagnosis, and treatment improves in tandem with technological innovation, gene therapies have the potential to become safe and effective treatment options for a wide range of genetic and nongenetic diseases. However, as the medical scope of gene therapies expands, consideration must be given to those who will benefit and what proactive steps must be taken to widen development and access potential, particularly in regions carrying a high disease burden.
- Subjects
GENE therapy; MIDDLE-income countries; TECHNOLOGICAL innovations; ROOT diseases; GENETIC disorders
- Publication
Science Translational Medicine, 2024, Vol 16, Issue 746, p1
- ISSN
1946-6234
- Publication type
Article
- DOI
10.1126/scitranslmed.adn1902