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- Title
Predicting VTE in Cancer Patients: Candidate Biomarkers and Risk Assessment Models.
- Authors
Riondino, Silvia; Ferroni, Patrizia; Zanzotto, Fabio Massimo; Roselli, Mario; Guadagni, Fiorella
- Abstract
Risk prediction of chemotherapy-associated venous thromboembolism (VTE) is a compelling challenge in contemporary oncology, as VTE may result in treatment delays, impaired quality of life, and increased mortality. Current guidelines do not recommend thromboprophylaxis for primary prevention, but assessment of the patient's individual risk of VTE prior to chemotherapy is generally advocated. In recent years, efforts have been devoted to building accurate predictive tools for VTE risk assessment in cancer patients. This review focuses on candidate biomarkers and prediction models currently under investigation, considering their advantages and disadvantages, and discussing their diagnostic performance and potential pitfalls.
- Subjects
THROMBOEMBOLISM prevention; THROMBOEMBOLISM risk factors; THROMBOEMBOLISM treatment; THROMBOEMBOLISM; BIOMARKERS; CANCER patients; RISK assessment; DIAGNOSIS; VEINS
- Publication
Cancers, 2019, Vol 11, Issue 1, p95
- ISSN
2072-6694
- Publication type
Article
- DOI
10.3390/cancers11010095