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- Title
Gut microbiota from infant with cow's milk allergy promotes clinical and immune features of atopy in a murine model.
- Authors
Mauras, Aurélie; Wopereis, Harm; Yeop, Intan; Esber, Nathalie; Delannoy, Johanne; Labellie, Chantal; Reygner, Julie; Kapel, Nathalie; Slump, Rob; Eijndthoven, Tiemen; Rutten, Lieke; Knol, Jan; Garssen, Johan; Harthoorn, Lucien F.; Butel, Marie‐José; Bajaj‐Elliott, Mona; Hartog, Anita; Waligora‐Dupriet, Anne‐Judith
- Abstract
Numerous clinical and epidemiological studies suggest an association between abnormal development of the gut microbiota in early life and development of clinical manifestations related to allergy including cow's milk allergy (CMA). Following oral allergen sensitization, CMA microbiota was associated with diarrhea-related symptoms (Figure A), with higher fecal scores (reflecting softer to diarrheic stools/ anal inflammation) that persisted at least 24 hours for the CMA-S group compared with HC-S group (P < 0.001).
- Subjects
GUT microbiome; IMMUNOGLOBULIN E; BUTYRATES; MILKING; INFANTS
- Publication
Allergy, 2019, Vol 74, Issue 9, p1790
- ISSN
0105-4538
- Publication type
Article
- DOI
10.1111/all.13787