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- Title
Cooperative mitogenic signaling by G protein-coupled receptors and growth factors dependent on G<sub>q/11</sub>.
- Authors
Kok Choi Kong; Billington, Charlotte K.; Gandhi, Uma; Panettieri Jr., Reynold A.; Penn, Raymond B.
- Abstract
Identifies the specific heterotrimeric G proteins that mediate cooperative mitogenic signaling by G protein-coupled receptors (GPCR) and growth factors in human airway smooth muscle (ASM) cells. Proteins that have been shown to promote mitogenic signaling by GPCR in various cell systems; Description of ASM mass; Types of GPCR that exhibit similar cooperative mitogenic effects with epidermal growth factor via a similar mechanism.
- Subjects
G proteins; GROWTH factors; MEMBRANE proteins; SMOOTH muscle; EPIDERMAL growth factor
- Publication
FASEB Journal, 2006, Vol 20, Issue 9, p1558
- ISSN
0892-6638
- Publication type
Article
- DOI
10.1096/fj.05-5622fje