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- Title
High Genetic Variability of Schistosoma haematobium in Mali and Nigeria.
- Authors
Ezeh, Charles; Mingbo Yin; Hongyan Li; Ting Zhang; Bin Xu; Sacko, Moussa; Zheng Feng; Wei Hu
- Abstract
Schistosoma haematobium is one of the most prevalent parasitic flatworms, infecting over 112 million people in Africa. However, little is known about the genetic diversity of natural S. haematobium populations from the human host because of the inaccessible location of adult worms in the host. We used 4 microsatellite loci to genotype individually pooled S. haematobium eggs directly from each patient sampled at 4 endemic locations in Africa. We found that the average allele number of individuals from Mali was significantly higher than that from Nigeria. In addition, no significant difference in allelic composition was detected among the populations within Nigeria; however, the allelic composition was significantly different between Mali and Nigeria populations. This study demonstrated a high level of genetic variability of S. haematobium in the populations from Mali and Nigeria, the 2 major African endemic countries, suggesting that geographical population differentiation may occur in the regions.
- Subjects
NIGERIA; BIOLOGICAL variation; SCHISTOSOMA haematobium; MICROSATELLITE repeats; ALLELES
- Publication
Korean Journal of Parasitology, 2015, Vol 53, Issue 1, p129
- ISSN
0023-4001
- Publication type
Article
- DOI
10.3347/kjp.2015.53.1.129