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- Title
A High-Linearity Glucose Sensor Based on Silver-Doped Con A Hydrogel and Laser Direct Writing.
- Authors
Hu, Yulin; Yang, Dasheng; Zhang, Hongbo; Gao, Yang; Zhang, Wenjun; Yin, Ruixue
- Abstract
A continuous glucose monitoring (CGM) system is an ideal monitoring system for the blood glucose control of diabetic patients. The development of flexible glucose sensors with good glucose-responsive ability and high linearity within a large detection range is still challenging in the field of continuous glucose detection. A silver-doped Concanavalin A (Con A)-based hydrogel sensor is proposed to address the above issues. The proposed flexible enzyme-free glucose sensor was prepared by combining Con-A-based glucose-responsive hydrogels with green-synthetic silver particles on laser direct-writing graphene electrodes. The experimental results showed that in a glucose concentration range of 0–30 mM, the proposed sensor is capable of measuring the glucose level in a repeatable and reversible manner, showing a sensitivity of 150.12 Ω/mM with high linearity of R2 = 0.97. Due to its high performance and simple manufacturing process, the proposed glucose sensor is excellent among existing enzyme-free glucose sensors. It has good potential in the development of CGM devices.
- Subjects
GLUCOSE; BLOOD sugar monitoring; BLOOD sugar monitors; HYDROGELS; DETECTORS; GLUCOSE oxidase; GLYCEMIC control
- Publication
Polymers (20734360), 2023, Vol 15, Issue 6, p1423
- ISSN
2073-4360
- Publication type
Article
- DOI
10.3390/polym15061423